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Tuesday 14 August 2007

Search curative of second liver immunity

Immune cure already developed gradually become a brand-new subject, it includes the content of two respects, it is immune adjustment, adjust with physics, chemistry and biologic method namely the immune function of airframe, make original immune function increases or abate; 2 it is immunity rebuilds, be about to what the hematopoiesis with immune normal and individual function does a cell or lymphocyte transplants to have immune function drawback is individual, make latter immune function normal all or the part gets resumptive. In " guideline of prevention and cure of chronic hepatitis B " in point out clearly also " one of important steps that immune adjustment cure is cure of chronic hepatitis B " . α interferon: α interferon has disease-resistant poison, fight tumor and immunity to adjust action. The immunity of α interferon adjusts action is very strong, still the immunity that enhances immunity to infect a cell to virus kills and wound active. α interferon returns what can enhance huge bite cell to gobble up function and cellular poisonous active. Clinical cure dosage is 3 million ~ 5 million unit, every week 3, period of treatment 3 ~ 6 months. Lasting curative effect is 25% ~ 40% . Common harmful response is flu appearance symptom, be like: Calorific, have a headache, joint and muscle ache. Get together glycol interferon is opposite take the place of in medicine at groovy interferon kinetic with the frequency that use drug second on have very big a kind of improved interferon, clinical research shows as a result get together glycol interferon was treating respect of chronic hepatitis B to show encouraging result. Thymus peptide: Thymus peptide preparation is the polypeptide material of thymus, it is had make the T lymphocyte become divided, proliferous, action; that improves cellular immunity function still can activation to kill and wound a cell naturally active and promote the cellular factor related to immunity to be like leucocyte interpose element 2, α and γ interferon the generation that wait. Commonly used thymus peptide preparation basically is thymus peptide α 1, thymus peptide α 1 it is artificial complex, contain the polypeptide of 28 amino acid, treat fine of all without exception in the process to react, chronic to cure hepatitis B has certain curative effect, fight virus medicaments to apply jointly with other more. Zun Xuanmi Zun: Zun Xuanmi Zun is a kind of effective immunity conditioning agent. Use at in recent years clinical the agent of Tu Bu of Zun Xuanmi Zun that go up, but outside surface of Tu Yu skin, daub after 72 hours, medicaments absorptivity is in 90% above, have improve cellular immunity and humoral immunity function, dosage is 5 milliliter, besmear trunk reachs limb skin surface outside, maintain 24 hours not scour off, every week 2 ~ 3, period of treatment is 6 months. Research confirms, vaccine of hepatitis B of combination of Zun Xuanmi Zun is mixed to patient of chronic hepatitis B the person that hepatitis B virus is carried has remedial effect, and without apparently harmful response. Pan gives birth to fourth operable BCG vaccine: According to Beijing University the first hospital affects disease division Si Chongwen to report, pan Shengding can give birth to interference to help each other fully in human body, play disease-resistant poison reachs immune adjustment action. Remedial method is Pan Shengding 25 milligram profess to convinced, daily 3, at the same time at antebrachium deltoid BCG vaccine of the inject inside the skin 0.1 milliliter, every months 1, period of treatment is 6 months. The beard before inject makes tuberculin test, with 1 ∶ 2000 tuberculin 5 units. If the skin tries eventuate negative or scleroma 19 millimeter person, can inject BCG vaccine, unripe Ding Ke of Pan of profess to convinced causes giddy, facial tide red reach glowing feeling, but this therapeutics price is low, have certain curative effect to chronic hepatitis B, for its advantage. Immune ribonucleic acid: It is intensifier of a kind of immunity, use at the auxiliary cure of chronic hepatitis B, the patient that can make function of partial cell immunity low returns to normal, clinical get used to card and move factor likeness. Treat chronic hepatitis method: Inject 1 times every week, every time 1 (3mg); period of treatment is 4 ~ commonly 6 months. 6 months above person instead injects 2 weeks 1 times, the longest for 1 year. Do not have apparently harmful response commonly, a few patient has Wei cold, calorific, rash. Clew: Immune ribonucleic acid still lacks strict, scientific clinical research data, affirm its curative effect still hard. Transfer gene: Transferring gene is material of young member of a kind of polynucleotide that makes from the extraction in healthy person leucocyte and polypeptide, for cellular immunity accelerant. Have can obtain distinctive with the cellular immunity function with distinctive blame, can promote release interferon. Dosage is 2 ~ 4 milliliter, hypodermic or inject all round lymph node, every week 1 ~ 2, period of treatment 2 ~ 3 months. Harmful response has Wei cold, calorific, whole body unwell, rash and skin Sao are urticant etc. Treat sexual vaccine: This is one kind breaks immunity of airframe of patient of chronic hepatitis B to be able to bear or endure the treatment that gets condition and response of immunity of activation T cell is politic, the good qualities that researcher also claims to treat sexual vaccine is " church " system of human body immunity identifies correctly " the enemy " , the immunity that breaks airframe is able to bear or endure accept position, produce oneself antibody, reduce the hepatitis B virus inside cleared even body. However, it is transitory that home's vaccinal to treating a gender research also is like, did not see further story. DNA vaccine: The data shows, vaccine of hepatitis B DNA ever caused wide attention, after having researcher Ceng Xian at small rat, turn gene rat and Beijing duck have a test, proof DNA vaccine has stronger cellular immunity reaction and antibody respondent; however, in subsequently I period the vaccinal to DNA report in clinical trial is less. (the exercitation edits: Plum apricot)

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