Protect liver to taste use undeserved the liver that turn over an injury

Relevant expert yesterday points out: The health care that protect liver tastes the psychology that just catered to the person that drink to need, long-term excessive is taken " 100 kill without one benefit " . Gong of ill expert of liver of province people hospital makes bright teach the introduction, examine in outpatient service in, because of drinking the dinner party causes " alcohol liver " the patient is in grow in quantity, already became the 2nd big hepatic killer after hepatitis of afterwards virus sex. Because alcohol basically passes hepatic metabolization, excessive drink to not allow to ignore to hepatic harm. Family of emergency call of total hospital of Wuhan of Guangzhou military region is the closest 3 days, close treated 38 alcoholism patients, cause the effect of different level to hepatic metropolis. A man that has used the health care that protect liver to taste says, "No matter the canal is used bad to say, always felt to eat to want stronger than eating. " 　 Professor Gong Zunjiong expresses, the health care that protect liver is tasted allege adjust hematic fat, to chemical sex liver injury has auxiliary protection effect. But if be taken for a long time, will naturally cause harm to oneself, and the person that these health care taste li of contains root of herbaceous peony to be not worth to liver shade has the effect that protect liver, be just the opposite to what one wished to the person of other constitution. Accordingly, "Abstinence protects liver " just be the most scientific method. Whether to have effect to protecting liver health care to taste, a health care that does not wish to disclose a full name tastes course of study wife person discloses, actually it just needs to cater to the psychology of the person that drink. (the exercitation edits: Plum apricot)

How does second liver change his appearance to do?

China is global second liver and patient of cancer of the liver's most country, occupy global 1/4 about. A few days ago, the countrywide second liver that precaution of disease of Ministry of Public Health controlled Hao Yang of bureau deputy director general to announce Ministry of Public Health to was begun 2006 epidemiology findings, antigen of surface of liver of second of 59 years old of crowds carries 1 ～ of countrywide rate for 7.18% , calculate accordingly, the person that antigen of surface of liver of completely state-owned second is carried makes an appointment with 93 million person, patient age is in mostly 20~50 year old, situation of second liver prevention and cure still austere. Be able to bear or endure medicine accentuates easily patient disease and 　 of psychological burden 　 " guideline of second liver prevention and cure " point out clearly, the overall objective that chronic hepatitis B treats is: Utmost ground is restrained for a long time or eliminate second liver virus. However, be able to bear or endure the obstacle that medicine became implementation of second liver patient to treat overall objective however, also become the bottleneck that poison of second liver disease-resistant treats at the same time. Teach the introduction according to Zhuang Hui of academician of Chinese Academy of Engineering, chronic second liver needs long-term treatment, if undertake nucleotide kind the disease-resistant poison of medicaments is treated, the patient needs time two years at least, and in fact the time with the patient longer need of 88% . Long-term remedy certainly will increases disease-resistant bane content to be able to bear or endure medical risk. Be able to bear or endure once medicine happens, can lose curative effect or curative effect to reduce to the remedy with effective virus originally, cause patient virus to rebound then; at the same time, be able to bear or endure after medicine change medicine or add medical treatment, increase patient happening multiple be able to bear or endure medical risk, the patient also will bear heavy psychological burden and mental pressure, serious negative sentiment can bring about illness accentuation. In addition, be able to bear or endure the remedial expenses that medicine causes rises, also reach aggravating patient burden of its family economy. Center of sanitation of spirit of hospital of famous psychology expert, Mount Hua applies Shen Xun to teach the introduction, the second liver patient of 60% above fears the disease has a relapse, and be able to bear or endure the culprit that medicine causes these concern and all fear just about. Beyond question, be able to bear or endure medicine already caused second liver patient to be carried in the double tax of disease, mentally. Expert of mutation of virus of precautionary second liver gives out 3 big politic 　 prevent and cure to second liver virus, the expert gives out virus is able to bear or endure medical mutation prevents 3 old strategy: 1. Logical choice nucleotide (acerbity) analogue fights what virus treats to get used to card. 2. Poisonous to having disease-resistant cure gets used to the patient of card, if choose nucleotide (acerbity) analogue, choose disease-resistant poisonous action when initiative cure as far as possible strong, be able to bear or endure the medicaments with medical mutation low occurence rate. The newest and clinical data that published on European liver ill annual meeting on April 26, 2008 shows: Use favour of patient of chronic second liver replaces Ka Wei 96 weeks, the patient virus that has 79% carries a quantity to fall to cannot measure a level. 3. Raise sex of patient comply with, using nucleotide (acerbity) during analogue undertakes disease-resistant poison is treated, should follow the doctor's advice on time, full amount takes drug, restrain virus as far as possible in lowermost level, do not give virus the chance of stage a come back. In addition, still should detect regularly during cure, every 3 months detect HBV-DNA level. (the exercitation edits: Plum apricot)

Open the myth that second liver cures

Clinical cure second liver and not be equal to effect a radical cure, the premise that; accepts treatment in a large number of patients leaves the possibility that they still have recrudesce, 103 achieve this kind of effect to cannot show any problem 　 Gu Jidong feels very helpless. The palm door person that learns liver disease to learn branch as China cure, his these days must not differ another come ahead everywhere the second liver patient of ask and media reporter explanation: We never had been released " second liver is clinical cure " message. Its origin on January 13. That day, media reports " 103 second liver patients of Chinese came true clinical cure " , "Pick off the cap of second liver " , and specialize this one message originates disease of liver of China cure society learns foundation of branch and Chinese hepatitis prevention and cure. "Second liver can be cured! " the great attention that this one report caused the public. A lot of patients begin to seek testimony everywhere, ask specific remedial method and remedial fee. This invites second liver experts only then makings do not, also feel anxious fully. Many people criticize exaggerate of this one message, have the ill will of misdirect patient. They are not worth the report of 1000 words to be able to cause so big effect first without expect. Clinical cure unlike effect a radical cure 　 　 in the message January 13 most " resounding " the place is to report first undoubtedly " liver of large quantities of second of patient pick off ' cap ' , have infectivity no longer, came true clinical cure " . A lot of people know, since Bulinbaige was in the biologist 1964 Australian native discovers second liver virus on the body (thinking at that time is local place is peculiar, also call antigen of second liver surface so " bay fight " ) since, capture second liver is the difficult problem of medical bound all the time. Chinese Ministry of Public Health wrote 2006 " point of knowledge of education of conduct propaganda of liver of precautionary control second " in special also make clear, "Infection of second liver virus still does not have ideal particularity to treat medicaments, domain of medical science and technology also has not capture some media advertisement is publicized ' turn shade ' ' effect a radical cure ' wait for difficult problem " . So, whether to mean second liver this to had been captured by medical bound? "This and capture second liver is having great difference. " a second liver expert that does not wish to disclose a full name says, "Capture second liver is to show the disease gets effecting a radical cure, and of second liver clinical cure and effecting a radical cure is two things completely. " this expert explains 　 further say, tell from medical angle, wanting exterior symptom to disappear only is clinical cure; and effect a radical cure mean the second liver virus inside thoroughly cleared body, both existence substantially distinction. After effecting a radical cure, won't have a relapse again, and clinical the symptom that curing is a disease gets controlling, but the possibility that still has recrudesce. 103 second liver is clinical the person that cure has 23 to come from Beijing bless to bring a hospital. This courtyard needs professor of month of division director Chen Xin to admit especially, these 23 patients cannot say to be cured thoroughly, it is them only the virus quantity inside body is controlled be in very low-level, as to whether can have a relapse again later, "Remain longer observation " . Accordingly, although these second liver patients came true through cure clinical cure, but do not wait to be cured thoroughly at getting (effect a radical cure namely) , still have recrudescent possibility. "103 " do not provide conviction 　 to be obtained this clinical 103 cured patients, all accepted a kind to be called the remedial program that sends Luo Xin. This kind is based on the disease-resistant poisonous cure that immunity rebuilds, main support grows effect interferon to disturb virus to duplicate, control virus amount, the immune system of human body oneself activations in the meantime, achieve the goal of antagonism virus. Clinical go up to had been made clear, antigen of second liver surface is serological changeover is immunity of patient of chronic second liver rebuild, the mark that moves toward rehabilitation. January 13 report, these patients treat plan through accepting clique collect glad, realized exterior antigen serological changeover (namely exterior antigen turns shade) . Disease of liver of China cure society learns branch standing member Professor Jiang Jiaji say: "Exterior antigen turns shade is the best curative effect that at present second liver cure obtains. " but Professor Jiang points out at the same time, this does not mean clique collect glad to be able to let all second liver patients get clinical cure. Most crucial is, these 103 person that cure are only " element " , but " denominator " -- shared how many patient to accept this kind of treatment after all -- do not have a report however. Without reliable clinical case count, this 103 without any conviction. 　 of of each has his strong point of two kinds of medicaments is current, capture the biggest obstacle of second liver is cannot kill second liver virus thoroughly. The detector cloth Lin Baige of second liver virus thinks, because,this basically is second liver virus too " tricky " , after they invade human body, the meeting is very quick be together with the DNA conformity of liver cell, make the immune system of human body takes these " the enemy that mixes in common people " in a dilemma: Or is patient their existence; or nots hesitate " the fault is killed innocent " eliminate them. Medical home discovers, itself of second liver virus does not cause the pathological change of liver cell directly, but once virus suffers the attack of immune system, liver cell can be destroyed at the same time, and because increase and relapse of immune function,this process often is met undertake, make hepatic organization suffers more and more destruction finally, occurrence liver is sclerotic even liver fails. Accordingly, the target of second liver cure with accepted bound of current medical science is not " virus of liver of thoroughly cleared second " , also not be " reduce transaminase level " " ' big 3 this world ' turn shade " , however utmost ground restrains virus for a long time, defer disease progress to become liver cirrhosis, liver cancer. Disease-resistant poison treats the key that becomes liver of current treatment second. "A lot of patients do not know disease-resistant poison is treated before, they take a few drug that protect liver, fall enzymatic medicine, spent a lot of money in vain. " saying of this word is biology of cause of disease of college of medicine of Beijing University foundation is academician of professor Zhuang Hui. The accepted disease-resistant bane owner on international should have two kinds. One kind is nucleotide analogue, include rummy husband to decide, the; such as Adefuwei is interferon another kind. Sending Luo Xin is interferon of a kind of lasting effect, the company of the pharmacy that cross a state that its manufacturing business is famous group of collect family name. In the United States and European Union country, lasting effect interferon began to be treated with virus of Yu Kangyi liver 2000. Clinical research confirms, through interferon cure, have 3% ～ really the patient of chronic second liver of 5% can achieve antigen of second liver surface to turn shade. The reporter confirms, on January 13 " second liver is clinical cure " the message is coming from at Shanghai limited company of pharmacy of collect family name is in " liver is ill 2007 forum " on constituent media is communicated meeting, and those who be not forum sponsor unit China cure to learn liver disease to learn branch, also not be foundation of prevention and cure of hepatitis of supportive unit China. A doctor that has contacted these two kinds of medicaments says, nucleotide says only in the message kind the defect of medicaments " period of treatment is not fixed, arise possibly still be able to bear or endure property of a medicine " , do not carry nucleotide however kind the advantage of medicaments, but mentioning clique collect glad is an advantage only, do not say its weakness however, have apparently break evenhanded. In fact, lasting effect interferon suits a crowd finite, still have certain undesirable reaction, and remedial cost is higher. Gu Jidong compares these two kinds of drug is orange and malic relation, each has his strong point. The most important is, nucleotide analogue and interferon have to nod jointly: Cannot ensure make patient of chronic second liver is achieved clinical cured target. Old crescent teachs an explanation to say, 23 when this Beijing bless installs a hospital to be collected clinical the person that cure, not be the trial measure that has planned beforehand, do not have exact to using the patient that sends Luo Xin to undertake count so. These are clinical the majority before this has accepted the person that cure to treat a method otherly, after instead sends Luo Xin to treat, appeared clinical cured effect, can say only " they are luckier " . In fact, the antigen of surface of chronic second liver with stable illness is electropositive person do not make an appointment with those who 1% is control every year to turn via any cure shade. China has the second liver patient of 30 million, 103 achieve this kind of result really no wonder. "Take off deficient overnight " a patient tells not actual 　 the reporter, see " second liver is clinical cure " after the message, think second liver had law to heal eventually formerly, look " it is empty glad " . He says, last time " glad " just just go a few months. Last year on October 22, bulletin of ministry of national science and technology says China treats vaccine of sexual second liver to obtain significant progress. This patient also thinks those who longed to cope with second liver " ultimate weapon " . Just can understand later, vaccine of liver of remedial sex second walks out of a lab, the most hopeful estimation also needs 5 ～ 10 years time. The mood of very sickish at that time person " begin to rise flightily " , the liberation army 302 hospitals combine traditional Chinese and Western medicine memory of Liu Shijing of director of liver ill division says, a few patients " the remedy that wants to stop to be being used, change current remedial plan " . Zhuang Hui academician says: "Even if is to be able to be used at clinical, the effect that treats vaccine of sexual second liver is told very hard also. " 　 and second liver patient expect what form bright contrast eagerly what cure is their exceeding deficient to second liver knowledge. Published 2005 " current situation of acknowledge of patient of Chinese second liver considers to report " show, the patient that the affects; to have 62% patient that the patient of 1/3 does not understand second liver to cause ill prime cause is second liver virus will treat eye demarcate to have 33% even to reduce transaminase level; looks cure demarcate is highbrow " complete and cleared second. An elder liver ill expert says, a lot of patients place the hope that cures second liver plant in some on new drug, after imagining new drug to appear on the market " take off deficient overnight " , immediately liver of pick off second " cap " . This is not actual, because capture the road of second liver still very endless. This is a lot of second liver patients cannot treat cure correctly probably, always be immersed in " disappointed - glad - disappointed " the reason place of odd group. (the exercitation edits: Plum apricot)

How long does the period of efficacy of second liver vaccine have?

Our country is current and clinical use second liver vaccine is gene project vaccine, it is a kind of safe and effective goods, side effect is little. After liver of second of human body have an inoculation is vaccinal, produce antibody through active immunity means, make human body gains the immune strength of pair of second liver. Statistical data makes clear, antibody of surface of liver of second of the human body after vaccinal second liver is vaccinal (fight one HBs) to turn positive rate is in 95% above, protect effectively period in 5 years of above, antibody drop is spent taller, immune force is more powerful, immunity protects duration to also grow more. But also few number person is in after vaccinal second liver is vaccinal, of the generation inside body fight - HBs drop is spent very low, short of protects a value, be affected with respect to what cannot prevent second liver virus effectively so and duplicate. Additional, after second liver vaccine is vaccinal, fight - HBs follows time elapse, drop degree can drop gradually, should fight - HBs drop is spent fall to be worth to protection the following when, also have immune power to second liver virus no longer. Accordingly, to assure to prevent the effect, after vaccinal second liver is vaccinal, should exsanguinate assay, check 2 half-and-half, if fight - HBs shows masculine gender, show vaccinal success, still should check at the same time fight - HBs drop is spent. If fight - HBs drop spends highest value to be 10 ～ 100mIU/m1 only, best 1 times in the multiple cropping after 6 months; is fought - when HBs drop spends highest value to be 101 ～ 1000mIU/ml, should at first the 1 ～ after have an inoculation inside 2 years answer measure fight - if HBs; is fought - HBs is when 1001 ～ 10000mIU/ml, should be in 2 ～ inside 4 years answer measure; to should be fought - when HBs is more than 10000mIU/ml, but in 4 ～ inside 6 years answer measure; to be fought when discovery - HBs drop is spent under multiple cropping answers when 10mIU/ml, multiple cropping still undertakes by the dosage that plants first and time plan. What Gao Di spends arise to fight after still having vaccine of liver of second of have an inoculation of small number of people - HBs, but still contracted hepatitis, is this why? Because second liver virus is a kind of virus that mutates highly,basically be, after it produces mutation, can turn the virus of new structure, new property into mutation body, the antibody inside former put oneself in another's position does not have immune force to new mutation individual plant, lost precautionary action. Have an inoculation of second liver vaccine is the reliable method that prevents second liver, but also not be absolutely with get sth done once and for ever. Have an inoculation must examine after have an inoculation the effect and fight - HBs drop is spent, and the basis is fought - HBs drop spends a circumstance timely answer measure, should drip degree when be less than protection to be worth, want seasonable reseed, make often keep effective inside body fight - HBs drop is spent, such ability prevent second liver virus effectively to affect, achieve the goal that prevents second liver truly. (the exercitation edits: Plum apricot)

Luobukaweike treats chronic second liver

Be in all sorts of video in learning to check a technology, CT can reflect hepatic pathology configuration performance most, if have inside the size shape of focus of a disease, place, amount and focus of a disease,do not have haemorrhage necrotic, calcify. From the brim of focus of a disease the circumstance can understand his to invade a gender, if brim of focus of a disease is smooth clear, show coating especially, show tumor grows relatively slow, if tumor border is punch-drunk,invade sexual small; , show tumor has taller descent quality, easy encroach blood vessel, or cancerous bolt is formed inside portal vein. The former liver cancer that send a gender can divide commonly according to general pattern for 4 model: Gigantic piece model: Cancerous organization submits chunk form, can be individual gigantic piece, the diameter is in 5cm above, also can become by a lot of concentrated nodal confluence, can have sometimes all round its come loose smally in tubercle, call huge chunk satellite; tubercle model: Cancerous tubercle can be individual or many, size differs, distributing in liver left, right leaf, also know exactly about sth nodal confluence becomes 　 of a bigger nodal; huge cake section (mix model) : Point to gigantic a companion individual or 　 of; of many nodal focus of a disease diffuses model: This model the scarcest, whole liver has diffuse the petty cancer that distributing is nodal. The growth that presses tumor means, there are two kinds of kinds on pathology, one kind is infiltration grows model, one kind is to expand grow model. Plan bound is not clear between former focus of a disease and liver essence, border of latter focus of a disease of brim faintness; is clear, or coating having a holiday is formed, these two kinds of types have different show on CT. Cancer of the liver often violates vein system, portal vein relatively liver vein and vein finishing speech more often be encroached. Vein suffers encroach can cause cancer the move inside swollen liver and form tumour bolt and fistula of activity arteries and veins. The liver cancer that grows around liver door often encroachs bile duct, bring about block sex icteric. Lymph node is transferred and many seeing, the lymph node after door of liver of main drag in and peritonaeum. Cancer of the liver can encroach adjacent organ directly. Move can cause ascites of courage and uprightness to peritonaeum, far is transferred with lung the commonnest. Cancer of the liver can produce spontaneity haemorrhage, form haematoma falls with coating inside liver or cause celiac internal haemorrhage. The CT expression of the former liver cancer that send a gender depends on not only the pathology of tumor sheds kinetic characteristic with blood, still with all round the liver organization condition that did not violate is concerned. CT is smooth sweep expression of great majority liver cancer to be low density, namely density of focus of a disease (CT is worth) relatively all round normal liver essence is relatively low, also can be wait for density or mix density, smooth sweep cannot discover. The person that high density is spent is very few, constant companion has fatty liver. Normally the focus of a disease of ≤ 1cm, the density difference with liver essence is very little, smooth sweep check to go out rate is very low (20%-40%) . When cancer of the liver and the density difference that normal liver organizes are lesser, need to use narrow window and adjust a window observation. But with narrow the window can bring about false positive. Density of cancer of the liver constant inhomogenous, lower density area is seen in low density focus of a disease, for sex of necrotic, bursa changes inside focus of a disease or adipose and metamorphic be caused by. The CT value of adipose and metamorphic area often is less than - 10Hu. Internal haemorrhage of focus of a disease is scarcer, expression is low density there is spot in focus of a disease piece shape high density spends an area. The density of a few liver cancer is evener, this is common at lesser and necrotic and unidentified the liver cancer that show. The liver cancer that is located in liver periphery can make the outline limitation apophysis of liver. The brim of cancer of the liver is mostly ambiguous and not only whole, there can be space to show picture of strip low density inside cancerous kitchen. Expand grow model focus of a disease, no matter nodal or gigantic piece model, attrib border all clear, major coating having a holiday exists, on CT expression is circuit is low all round tumor the annulus shadow of density (namely dizzy annulus asks for) , ply can differ to 1cm from several Mm, it is especially in small liver cancer commonner. The coating on pathology is formed by fibre. The prognosis of the person that have coating relatively the person that do not have coating is good. When discovering because of the liver cancer that does not have coating, although lesser, but often already bolt of the cancer inside portal vein and its branch is formed. The calcify of cancer of the liver is not common, can submit concentrated drop record, radiation shape, line shape or irregular form. Groovy CT examination goes after increasing, the low density focus that expression of major liver cancer heightens to spend aggrandizement door gently to have) or not aggrandizement, as a result of all round aggrandizement of normal liver organization is more apparent, it is more clear that reason shows to the configuration of focus of a disease, size. (the exercitation edits: Plum apricot)

Is globulin of second liver immunity hit? Do not hit?

Nbsp;nbsp;nbsp;nbsp; our country is area of hepatitis B tall hair, have 1. Sicken of 200 million person; And in a variety of causes that cause this one astonishing number, mother baby transmission is the mainest -- , the patient that has 40% because this catch a disease. This brought an issue: How should we break transmission of baby of second liver mother to assure the child's health through block, thereby pick off " second liver big country " cap? Come for years, the method of the globulin of immunity of liver of second of pregnant woman inject that a lot of hospitals collected draw to affect second liver, but, as a result of a variety of reasons, this kind of practice suffers controversy all the time in academia. Recently, ministry of medicine of academician of Chinese Academy of Engineering, Beijing University teachs Zhuang Hui to prevent height forum to went up to put forward crosscurrent clearly in hepatitis B immunity, make this problem makes the central point of attention again. Is globulin of second liver immunity used very generally what is globulin of immunity of 　 second liver? Be in hospital of Beijing ground altar, dr Li Ping of department of gynaecology and obstetrics tells a reporter, immune globulin is the normal material inside human body actually, it can counteract the cause of disease that enters human body microbial, include bacterium and virus. Globulin of second liver immunity is extracted from inside the blood of normal person, have the capacity of virus of liver of the second in counteracting blood. "This from begin to use 10 years ago. " she says, pregnant woman is pregnant 28 weeks or so begin to hit globulin of second liver immunity, it can enter fetal system inside, neutralize the second liver virus that enters fetal blood, reduce the odds that affects inside second liver palace greatly. When the reporter asked about the person that whether comes here to use globulin of second liver immunity, dr Li Ping says: "The pregnant woman great majority that come here was used. It is right ' small 3 this world ' block is broken rate amount to 95% , right ' big 3 this world ' the possibility is a bit a few smaller. " nevertheless, she did not tell a reporter whether this is normal statistical number. Reporter phone contacted university of traffic of director of institute of hepatitis of Xi'an traffic university, Xi'an the first hospital infects division director Zhang Shulin, he is home one of experts that study globulin of second liver immunity earlier. Professor Zhang expresses, he is from what begin to undertake globulin of second liver immunity studies 15 years ago, and home is large-scale using is from 1995, the left and right sides began 1997, "Current, the method that total national capital had used the pregnant woman that gives infection second liver to hit immune globulin " . Guideline of second liver prevention and cure did not make conclusions a doctor of 302 hospitals is accepting 　 liberation army when the reporter is interviewed, say, it is the second liver that announces according to the country to affecting the pregnant woman of second liver to use immune globulin guideline of prevention and cure comes, announce inside countrywide limits use a kind of drug, showing it is " well-founded, not be blind " . But, the situation that the reporter understands is not however such. Last year year end, branch of epidemiology of China cure society and liver ill credit can roll out Chinese head ministry " guideline of prevention and cure of chronic hepatitis B " , the prevention and cure of liver giving second placed reference standard. But the reporter notices, the pregnant woman that this guideline did not allude to affect second liver hits immune globulin this one. Si Chongwen of professor of division of disease of infection of the first hospital tells committee member of advisory committee of expert of hepatitis of sex of virus of Ministry of Public Health, Beijing University the reporter, because academia is too intense to the controversy of this one problem,this is, do not have final conclusion temporarily so. Academia debate is intense 　 controversy has many intense, why and controversy? The reporter in interviewing discovers, the controversy basically centers in the following: One, authority is recommended. Professor Zhuang Hui tells a reporter, ministry of Public Health of World Health Organization, our country and the professional society that second liver prevents and cure did not recommend the method that will prevent baby of second liver mother to travel through giving pregnant woman inject immunity globulin, other country never also has taken this kind of way. But Professor Zhang Shulin thinks, second liver patient basically is in China centrally, it is very normal that foreign He Shiwei was not recommended. Did not recommend as to our country Ministry of Public Health, still basically lack the support of test data. 2, clinical trial. Respecting this, professor Si Chongwen thinks, lack " evidence " be " globulin of immunity of liver of second of pregnant woman inject " one of keys that inadequacy is a letter. To this, professor Zhang Shulin also admits, still do not have at present strict according to medicines and chemical reagents clinical trial administers a standard (GCP) the action that the experiment of the travel that enter 　 will come to prove to hit immune globulin to travel to preventing second liver Mu Ying to pregnant woman, more returning is " it is severally blast " small-scale test. "The hope can have brushstroke fund, make us OK undertake large-scale random double blind contrasts experiment " . 3, material curative effect. Although lack experiment support, but Professor Zhang Shulin emphasizes: The second liver block of globulin of immunity of use second liver is broken businesslike taller than what did not use. According to report of Xinhua News Agency, 2000, fudan University college of medicine is accessary and paediatrics the Zhu Qi of the hospital the professor ever pointed out when the way that puts forward to hit immune globulin to pregnant woman, be pregnant oneself 28 weeks rise, the puerpera hits stitch immunity globulin every months, rate of the infection inside second liver palace of the baby is met by 14 original. 7 ％ drop 5. 7 ％ . Nevertheless, professor Zhuang Hui points out in the letter that gives a reporter: To liver transplanting patient, its are hepatic (the main room with second liver duplicate virus) already was excised, below this kind of circumstance, euramerican country still suggests: Have a relapse to prevent second liver, should inject in the operation immune globulin 10000 international unit (the dosage that far outclass home injects to pregnant woman) , and inject even for long after art, be in in order to make antibody of surface of liver of the second in blood is maintained be more than 100, the level of 500 international unit. Although such, still have recrudesce of liver of second of patient of transplanting of one part liver. The liver of pregnant woman was not excised, virus still duplicates in great quantities inside liver, the dosage of globulin of second liver immunity of inject very low, remove block impossibly to decide the effect that Mu Ying spreads. 4, virus mutates. In interview, professor Zhuang Hui and Professor Si Chongwen point out, evidence shows, to patient of liver, kidney transplant globulin of immunity of liver of many inject second is met bring about virus to mutate, the likelihood makes " active vaccine cannot prevent second liver " . But Professor Zhang Shulin thinks, the quantity of the immune globulin that injects to patient of liver, kidney transplant and the amount that inject to pregnant woman are different. So old come, did not hear of because inject immunity globulin appears,have pregnant woman harmful response or cause infantile growth undesirable, more " the effectiveness that won't reduce vaccine " . 5, affect a way. This is the another core issue that should give pregnant woman inject immunity globulin. Professor Si Chongwen points out, understand according to him, in transmission of baby of second liver mother 95% it is to produce haemal infection, having 5% only is the infection inside palace -- , former through giving a baby inject vaccine and immune globulin, can have very good precaution effect, latter is the reason place that a lot of doctors make immune globulin to pregnant woman, think immune globulin can rise to prevent the action that influences inside palace. But Professor Zhang Shulin thinks, judge standard differs as a result. They are passed detect ribonucleic acid of to oxigenate of second liver virus (HBVDNA) discovery, the proportion that affects inside palace is as high as nearly 40% actually. Unite an opinion: Should hit 　 look back on to the baby, to globulin of second liver immunity, didn't academia unite a view really? The reporter understands, although be opposite,the pregnant woman that affects second liver should make exception of immune globulin existence, but experts think consistently: Should hit to the baby. Professor Zhuang Hui points out, if the mother affects second liver, new student 24 hours of a person operating from within in coordination with outside forces after be born inject as early as possible immune globulin, at the same time 10 microgramme recombine have an inoculation yeasty or liver of 20 microgramme second is vaccinal, such can effective block break transmission of baby of second liver mother. Can be born in the child additionally hind globulin of 1 needle immunity injects first inside 12 hours, the 2nd needle injects again after a month, at the same time vaccinal 10 microgramme recombine 1 needle yeasty or 20 microgramme are vaccinal, lie between a month and 6 months to part again vaccinal, before block breaks rate comparing one kind of measure is expensive. He still expresses, if new student in be born 12 hours inside injected immune globulin and vaccine, can accept maternal lactation. "Now is a child, hope can healthy. " in interviewing, professor Si Chongwen says to the reporter, be this kind of state of mind, the mother that lets many infection second liver chose to hit immune globulin before production. This also is one of reasons that this kind of therapeutics is able to popularize quickly. But, in view of lack credible test data, "Our manner still is to be not encouraged " . (responsibility edits: Zhang Jiong smooth)

Treat chronic second liver for nothing obviously

Our country has contracted second liver virus (HBV) person about 600 million person, 1. 200 million person becomes the person that chronic HBV is affected, chronic hepatitis is made an appointment with 30 million. 2002 statistic, virus sex hepatitis dies 65, 80 thousand, first what hold contagion death number. Reach relevant disease every year because of chronic hepatitis (liver cirrhosis, liver cancer) the immediate pecuniary loss that cause adds up to a RMB about 1122. 800 million yuan. In the meantime, a few gainful medicine unscrupulous merchant, fictional a lot of false advertisement, prevail on patient is deceived, or without any curative effect, or aggravating illness and even death. So, how to treat second liver for nothing obviously? Last year the end of the year, ill branch of liver of China cure society and home of organization of infection ill chapter concern an expert, referenced domestic and international newest research, according to the principle of abide card medicine, make piece " guideline of prevention and cure of chronic hepatitis B " . File of this creed sex, point out the optimal plan that treats chronic second liver to doctors, lest does not have Zhang Ke abide; Make the patient knows to treat the current situation of second liver at present, lest suffers false advertisement temptation, be deceived wasteful gold. The overall objective that treats chronic second liver at present is: Utmost ground is restrained for a long time or eliminate HBV, relieve liver cell inflammation the necrotic fiber that reach liver is changed, defer and prevent a disease to make progress, decrease and prevent liver to break the happening of cirrhosis of acting countervail, liver, liver cancer and its complication, improve the life thereby quality and extend surviving time. At present cure basically is disease-resistant poison, immunity adjustment, fight phlogistic protect liver, fight fiber to change etc, fighting virus among them is crucial. Chronic hepatitis is cured very hard, it is very important to maintain an illness to stabilize or do not develop. Any advertisement conduct propaganda can effect a radical cure or turn entirely shade is impossible, absolutely cannot try out. The remedial principle of all sorts of circumstances introduces below: 1. Chronic hepatitis B divides kind of case, traditional idea thinks HBeAg positive turns as its private parts is nice. Plan announces chronic second liver no matter HBeAg is in relief, r is born or HBeAg shade, r is unripe, want HBVDNA positive only, serum ALT lasts or relapse unusual, or liver organization examination has hepatitis pathological change, should cause take seriously. Such patient should be treated actively, need disease-resistant poison to treat especially, illness of ability keep within limits makes progress. 2. Be not the person that mobile sex HBsAg is carried, it is to point to sex of serum HBsAg day, HBeAg negative, fight HBe positive or negative, HBV DNA does not detect (PCR law) or detect under lowest be restricted, follow continuously inside 1 year visit above 3 times, ALT is in normal limits. To such patients of short duration need not be treated, but should monitor illness change, if last,HBV DNA positive accompanies ALT unusual, fight virus to treat with respect to Lv of take an examination. In clinical see these patients, a lot of by advertisement temptation or deceit, invest a large number of capital, treat the patient's condition of original stability worse more instead. Still can turn its without what medicaments at present shade. 3. The person that chronic HBV is carried, serum HBsAg and HBVDNA are electropositive, HBeAg or fight - HBe is electropositive, follow continuously inside 1 year visit above 3 times, serum ALT and AST all are in normal limits, liver organization examination is not had commonly apparently unusual. Had better do liver to wear to HBV DNA, so that farther diagnose is mixed,have corresponding treatment. This kind of patient cannot go with advertisement absolutely. 4. Hide a gender chronic second liver more and more be paid close attention to by people. One part patient has symptom of chronic second liver, but HBsAg is electronegative, can have fight, HBs, fight - HBe and (or) fight, HBc is electropositive, but serum and (or) the HBV DNA in liver organization is electropositive. Additionally 20 ％ hide a gender chronic second liver divides HBV, outside DNA positive, serological mark of the others HBV all is negative. Must not treat in disorder to such patients, answer to eliminate other virus and the liver that are not virus element to cause to damage further. 5. Sclerotic to liver patient should distinguish cirrhosis of liver of acting countervail sex and cirrhosis of liver of sex of the countervail that miss generation. According to HBeAg this world, quality, HBV DNA discretion, ALT is normal, liver function circumstance undertakes be judginged integratedly. This kind of patient must look for the specialized subject doctor that has experience to decide to treat plan, absolutely cannot oneself are treated in disorder. Anyhow, although this kind of patient uses active treatment, pathological changes also won't changeover, can rise to defer an illness to develop effect only. Anyhow, as a result of the stubborn sex of second liver virus, at present Shang Mogen studies a method. By domestic and international expert accepted the remedy that has certain curative effect, still be α , the disease-resistant bane content of interferon and nucleotide analogue. A lot of conduct propaganda treat second liver advertisement, such as size 3 this world turn shade medicine, ancestral secret recipe cures therapy of second liver, gene to treat second liver to wait, it is suspect, absolutely cannot excessive is treated. 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