Saturday, 11 August 2007
Open the myth that second liver cures
Clinical cure second liver and not be equal to effect a radical cure, the premise that; accepts treatment in a large number of patients leaves the possibility that they still have recrudesce, 103 achieve this kind of effect to cannot show any problem Gu Jidong feels very helpless. The palm door person that learns liver disease to learn branch as China cure, his these days must not differ another come ahead everywhere the second liver patient of ask and media reporter explanation: We never had been released " second liver is clinical cure " message. Its origin on January 13. That day, media reports " 103 second liver patients of Chinese came true clinical cure " , "Pick off the cap of second liver " , and specialize this one message originates disease of liver of China cure society learns foundation of branch and Chinese hepatitis prevention and cure. "Second liver can be cured! " the great attention that this one report caused the public. A lot of patients begin to seek testimony everywhere, ask specific remedial method and remedial fee. This invites second liver experts only then makings do not, also feel anxious fully. Many people criticize exaggerate of this one message, have the ill will of misdirect patient. They are not worth the report of 1000 words to be able to cause so big effect first without expect. Clinical cure unlike effect a radical cure in the message January 13 most " resounding " the place is to report first undoubtedly " liver of large quantities of second of patient pick off ' cap ' , have infectivity no longer, came true clinical cure " . A lot of people know, since Bulinbaige was in the biologist 1964 Australian native discovers second liver virus on the body (thinking at that time is local place is peculiar, also call antigen of second liver surface so " bay fight " ) since, capture second liver is the difficult problem of medical bound all the time. Chinese Ministry of Public Health wrote 2006 " point of knowledge of education of conduct propaganda of liver of precautionary control second " in special also make clear, "Infection of second liver virus still does not have ideal particularity to treat medicaments, domain of medical science and technology also has not capture some media advertisement is publicized ' turn shade ' ' effect a radical cure ' wait for difficult problem " . So, whether to mean second liver this to had been captured by medical bound? "This and capture second liver is having great difference. " a second liver expert that does not wish to disclose a full name says, "Capture second liver is to show the disease gets effecting a radical cure, and of second liver clinical cure and effecting a radical cure is two things completely. " this expert explains further say, tell from medical angle, wanting exterior symptom to disappear only is clinical cure; and effect a radical cure mean the second liver virus inside thoroughly cleared body, both existence substantially distinction. After effecting a radical cure, won't have a relapse again, and clinical the symptom that curing is a disease gets controlling, but the possibility that still has recrudesce. 103 second liver is clinical the person that cure has 23 to come from Beijing bless to bring a hospital. This courtyard needs professor of month of division director Chen Xin to admit especially, these 23 patients cannot say to be cured thoroughly, it is them only the virus quantity inside body is controlled be in very low-level, as to whether can have a relapse again later, "Remain longer observation " . Accordingly, although these second liver patients came true through cure clinical cure, but do not wait to be cured thoroughly at getting (effect a radical cure namely) , still have recrudescent possibility. "103 " do not provide conviction to be obtained this clinical 103 cured patients, all accepted a kind to be called the remedial program that sends Luo Xin. This kind is based on the disease-resistant poisonous cure that immunity rebuilds, main support grows effect interferon to disturb virus to duplicate, control virus amount, the immune system of human body oneself activations in the meantime, achieve the goal of antagonism virus. Clinical go up to had been made clear, antigen of second liver surface is serological changeover is immunity of patient of chronic second liver rebuild, the mark that moves toward rehabilitation. January 13 report, these patients treat plan through accepting clique collect glad, realized exterior antigen serological changeover (namely exterior antigen turns shade) . Disease of liver of China cure society learns branch standing member Professor Jiang Jiaji say: "Exterior antigen turns shade is the best curative effect that at present second liver cure obtains. " but Professor Jiang points out at the same time, this does not mean clique collect glad to be able to let all second liver patients get clinical cure. Most crucial is, these 103 person that cure are only " element " , but " denominator " -- shared how many patient to accept this kind of treatment after all -- do not have a report however. Without reliable clinical case count, this 103 without any conviction. of of each has his strong point of two kinds of medicaments is current, capture the biggest obstacle of second liver is cannot kill second liver virus thoroughly. The detector cloth Lin Baige of second liver virus thinks, because,this basically is second liver virus too " tricky " , after they invade human body, the meeting is very quick be together with the DNA conformity of liver cell, make the immune system of human body takes these " the enemy that mixes in common people " in a dilemma: Or is patient their existence; or nots hesitate " the fault is killed innocent " eliminate them. Medical home discovers, itself of second liver virus does not cause the pathological change of liver cell directly, but once virus suffers the attack of immune system, liver cell can be destroyed at the same time, and because increase and relapse of immune function,this process often is met undertake, make hepatic organization suffers more and more destruction finally, occurrence liver is sclerotic even liver fails. Accordingly, the target of second liver cure with accepted bound of current medical science is not " virus of liver of thoroughly cleared second " , also not be " reduce transaminase level " " ' big 3 this world ' turn shade " , however utmost ground restrains virus for a long time, defer disease progress to become liver cirrhosis, liver cancer. Disease-resistant poison treats the key that becomes liver of current treatment second. "A lot of patients do not know disease-resistant poison is treated before, they take a few drug that protect liver, fall enzymatic medicine, spent a lot of money in vain. " saying of this word is biology of cause of disease of college of medicine of Beijing University foundation is academician of professor Zhuang Hui. The accepted disease-resistant bane owner on international should have two kinds. One kind is nucleotide analogue, include rummy husband to decide, the; such as Adefuwei is interferon another kind. Sending Luo Xin is interferon of a kind of lasting effect, the company of the pharmacy that cross a state that its manufacturing business is famous group of collect family name. In the United States and European Union country, lasting effect interferon began to be treated with virus of Yu Kangyi liver 2000. Clinical research confirms, through interferon cure, have 3% ~ really the patient of chronic second liver of 5% can achieve antigen of second liver surface to turn shade. The reporter confirms, on January 13 " second liver is clinical cure " the message is coming from at Shanghai limited company of pharmacy of collect family name is in " liver is ill 2007 forum " on constituent media is communicated meeting, and those who be not forum sponsor unit China cure to learn liver disease to learn branch, also not be foundation of prevention and cure of hepatitis of supportive unit China. A doctor that has contacted these two kinds of medicaments says, nucleotide says only in the message kind the defect of medicaments " period of treatment is not fixed, arise possibly still be able to bear or endure property of a medicine " , do not carry nucleotide however kind the advantage of medicaments, but mentioning clique collect glad is an advantage only, do not say its weakness however, have apparently break evenhanded. In fact, lasting effect interferon suits a crowd finite, still have certain undesirable reaction, and remedial cost is higher. Gu Jidong compares these two kinds of drug is orange and malic relation, each has his strong point. The most important is, nucleotide analogue and interferon have to nod jointly: Cannot ensure make patient of chronic second liver is achieved clinical cured target. Old crescent teachs an explanation to say, 23 when this Beijing bless installs a hospital to be collected clinical the person that cure, not be the trial measure that has planned beforehand, do not have exact to using the patient that sends Luo Xin to undertake count so. These are clinical the majority before this has accepted the person that cure to treat a method otherly, after instead sends Luo Xin to treat, appeared clinical cured effect, can say only " they are luckier " . In fact, the antigen of surface of chronic second liver with stable illness is electropositive person do not make an appointment with those who 1% is control every year to turn via any cure shade. China has the second liver patient of 30 million, 103 achieve this kind of result really no wonder. "Take off deficient overnight " a patient tells not actual the reporter, see " second liver is clinical cure " after the message, think second liver had law to heal eventually formerly, look " it is empty glad " . He says, last time " glad " just just go a few months. Last year on October 22, bulletin of ministry of national science and technology says China treats vaccine of sexual second liver to obtain significant progress. This patient also thinks those who longed to cope with second liver " ultimate weapon " . Just can understand later, vaccine of liver of remedial sex second walks out of a lab, the most hopeful estimation also needs 5 ~ 10 years time. The mood of very sickish at that time person " begin to rise flightily " , the liberation army 302 hospitals combine traditional Chinese and Western medicine memory of Liu Shijing of director of liver ill division says, a few patients " the remedy that wants to stop to be being used, change current remedial plan " . Zhuang Hui academician says: "Even if is to be able to be used at clinical, the effect that treats vaccine of sexual second liver is told very hard also. " and second liver patient expect what form bright contrast eagerly what cure is their exceeding deficient to second liver knowledge. Published 2005 " current situation of acknowledge of patient of Chinese second liver considers to report " show, the patient that the affects; to have 62% patient that the patient of 1/3 does not understand second liver to cause ill prime cause is second liver virus will treat eye demarcate to have 33% even to reduce transaminase level; looks cure demarcate is highbrow " complete and cleared second. An elder liver ill expert says, a lot of patients place the hope that cures second liver plant in some on new drug, after imagining new drug to appear on the market " take off deficient overnight " , immediately liver of pick off second " cap " . This is not actual, because capture the road of second liver still very endless. This is a lot of second liver patients cannot treat cure correctly probably, always be immersed in " disappointed - glad - disappointed " the reason place of odd group. (the exercitation edits: Plum apricot)
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