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Thursday 28 June 2007

Not step the error of poison of second liver disease-resistant

Disease-resistant bane content belongs to prescription drug, its are optimal getting used to disease is HBVDNA positive, ALT fluctuate repeatedly the patient of liver of chronic activity sex in 100-300 unit. Our country is liver disease (the tall hair area that H B V) affects, chronic liver ill patient makes an appointment with 30 million person, partial patient can develop the sclerosis that it is liver or liver cancer of former hair sex. Treat a cause about chronic liverish, at present academia of international, home already reached consensus, restrain virus for a long time to duplicate namely, delay liverish progress! And reach afore-mentioned remedial goals, refusing ill poisonous treatment is crucial! But in clinical work, discover a lot of patients defy virus cure has the deviation on understanding, make a variety of errors exist in cure. 1 disease-resistant poison treats the error not matter the person that   is carried as a result of a lot of second liver virus is lifetime do not come on, this makes a few chronic liver that should accept treatment ill patient mistake nots matter to fight virus to treat, take when liver function is unusual a few fall enzymatic medicaments went. These patients do not wish for a long time go to a doctor, also do not wish to cooperate the doctor's system to treat, abandon what periodic liver function and virus learn index monitoring even, once be in a bad way and must when go to a doctor, often had developed be heavy-duty liver disease or liver cirrhosis is terminal. Error 2 did not get used to disease to use content of bane of medical   disease-resistant to belong to prescription drug casually, its are optimal getting used to disease is HBVDNA positive, ALT fluctuate repeatedly the patient of liver of chronic activity sex in 100-300 unit. But to achieve the goal of virus of cleared second liver proper motion buys the patient that often sees a few liver function are normal at present medical treatment, although the result that HBVDNA shade turns can be achieved in remedial initial stage, but after stopping drug, still can lift again, the result brings about virus happening to be able to bear or endure medicine, need disease-resistant poison truly in the patient even when cure, cannot choose significant curative thing. Say so, it is very wrong that patient proper motion buys medicine to treat with danger. When poison of disease-resistant of patient of 3 liver cirrhosis is the error, late already   has the illness of some of liver ill patient to had developed the cirrhosis that it is liver, appeared even the performance that the liver function such as haemorrhage of ascites, enteron, hepatic coma breaks acting countervail. These patients often lose confidence to cure, when thinking to fight ill poisonous cure to be late already. Actually, the clinical research that undertakes in liver cirrhosis patient disease-resistant poison is treated in recent years is in all have domestic and internationally begin, among them most authoritative research is to was published last year as a result in October " magazine of new england medicine " go up, applied rummy husband treats the patient of inchoate liver cirrhosis surely, can reduce progress of disease of liver of liver cirrhosis patient and the risk that reduce happening of cancer of the liver to amount to 50% ! In another research of abroad that have, the countervail missing generation that a few preparation accept liver to transplant patient of period liver cirrhosis, the remedy that rummy husband decides was accepted before the operation, after cure, the patient liver function that has 2/3 improves apparently, achieved even defer the effect of the operation. Poison of disease-resistant of 4 blind combination treats the error   a few patients keep clear of to achieve the purpose of liver ill virus, combine a variety of medicaments that fight liver ill virus blindly. Actually, the action mechanism of a few medicaments is identical. Have a few remedy additionally, although their action mechanism is different, but through in last few years clinical research, most expert did not see onefold the effect with use medicine to have better than combination with medicine. Medicaments of virus of antagonism of liver ill virus is very sensitive, treatment of thing of applied new student needs every months to cooperate inject stitch only, can achieve the goal that restrains liver ill virus to duplicate. In recent years accordingly most expert thinks, liverish disease-resistant poison treats medicaments not to answer blind and onefold application, and the order follow in a continuous line that another kind of medicaments changes again after should using content of bane of a kind of disease-resistant to use period of time treats a method. The HBVDNA drop of a few patients of   of mutation of 5 beyond the mark and scared virus spends the error very tall, liver function is long-term and unusual, but because they are beyond the mark scared virus mutates and dare not use disease-resistant poison to medication. Actually virus mutation is very regular job. For example flu virus, be in all the time produce mutation, because this people should make a new vaccine every year,undertake vaccinate. If liver ill virus is long use thing of bane of a kind of disease-resistant, virus can produce mutation, be born to products of this kind of drug be able to bear or endure medicine. Once virus is right,a kind of medicaments is able to bear or endure after medicine, can choose other remedy to continue to treat again, can make virus is restrained very quickly, liver cell is necrotic stop, liver function improves, prevented the progress that liver fiber changes, won time to be treated further or await more effective remedy to appear. (responsibility edits: Come Hui Li)

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