Poison of second liver disease-resistant treats " strategic tactics "

Common saying says: Be like resort to arms with medicine, the in principle that treating second liver also is " the person does not make me, I not if convict; person makes me, I need convict. " although we had said, the disease-resistant poison of second liver treats avoid by all means to use drug blindly. But unusually long-term to transaminase, the patient of hepatitis of chronic activity sex with duplicate and electropositive virus is different. If we regard second liver virus as " the enemy " , so, as a result of " the enemy " a large number of duplicating, had caused " we " the harm of liver cell, we cannot overlook. At the moment, we can want this to take disease-resistant bane matter " weapon " go hitting " the enemy " . Second liver virus this " the enemy " but tricky, when we are in and it fights, also should know a bit " strategic tactics " . Poison of second liver disease-resistant is able to bear or endure 　 of formulary case Nbsp; is not despised " the enemy " 　 because the tall hair area that our country is hepatitis B, the person that a lot of virus are carried is lifetime do not come on. Accordingly, make mistake of patient of a few chronic hepatitis B is: "Disease-resistant poison cure nots matter " , "Take when liver function is unusual a few fall enzymatic medicaments went " . These patients do not wish for a long time go to a doctor, also do not wish to comply with systematic cure of the doctor, abandon what periodic liver function and virus learn index monitoring even. This kind " underestimate the enemy " the thought often brought about a patient to arrive when be in a bad way, had developed even for heavy-duty hepatitis or liver cirrhosis terminal ability must go to a doctor, consequently incur loss through delay remedial opportunity. The person that really some of second liver virus is carried but all one's life do not come on. But the harm of second liver virus to human body often undertakes soundlessly inside body, patient of most and chronic hepatitis is spent gently in transaminase unlike of apparent symptom; is not had when lifting the cold has a fever or diarrhoea, him patient cannot judge him to whether should be treated according to his symptom. Accordingly, we often say second liver virus is the delitescent inside body " spy " , the person that hepatitis B virus is affected should keep vigilant at any time, check liver function and second liver virus to learn index to the hospital regularly, once discovery is unusual, should instantly go to a doctor, according to the doctor's cure plan undertakes disease-resistant poison is treated. Still one is plant " the enemy " cannot despise, it is false " small 3 this world " condition. Generally speaking, second liver virus affects " small 3 this world " condition is second liver virus is duplicate " winter sleep period " . At this moment, second liver virus is not had almost duplicate, liver function is normal, the patient's illness is relatively smooth, beardless cure. But part " small 3 this world " the patient relapses liver function is unusual, its reason may be the second liver virus that contracted mutation of area of the one C before planting. Such " small 3 this world " the patient although the E antigen in serum is electronegative, but the virus inside body is done not have " hibernant " , they also resemble " big 3 this world " duplicate ceaselessly inside body euqally (HBV DNA electropositive) , the illness still can make progress ceaselessly. Constant companion has the patient durative or intermittence serum transaminase is elevatory, bring about have sexual liver disease. Accordingly, the virus inside such patient system still needs disease-resistant poison to treat. The course fights virus to treat, the duplicate meeting of second liver virus is restrained very quickly, of liver cell necrotic also stopped subsequently. Should master " opportunity for combat " 　 and second liver virus " fight " the patient of hepatitis of chronic activity sex that optimal opportunity is HBV DNA positive, ALT is in 400 units of 100 ～ / or so litres. A lot of doctors had concluded in clinical practice: The curative effect of second liver patient with normal ALT is poorer. Accordingly, premature when liver function is normal " hit out " , as a result of system of the immunity inside body " enthusiasm " did not start rise, not only incontrollable " the enemy " , easy still " expose " our " weapon " , make the enemy " want " give the way that meets us, produce virus to mutate namely, generation is able to bear or endure medicine. If we " hit out " too late, "The enemy " be destroyed too badly to our liver, although we use disease-resistant bane thing this " weapon " can control temporarily " the enemy " , but liver also won't get very good rehabilitate. Additional, patient of cirrhosis of a few liver, the person that the liver, second liver of kidney transplant art is affected, the person that tumor changes cure period and the second liver infection that surround operation period gains an opportunity to give further surgery or treatment, also can use disease-resistant bane thing first, " the enemy " beat back " . Do not fear " the enemy " 　 a few patients too fear " the enemy " , fear especially the mutation of virus. So, although " the enemy " the liver that has given us was caused destroy, but dare not take namely " weapon " struggle with the enemy. Actually virus mutation is very regular job, without what terrible. All biology on the world can produce mutation. Because the mankind wants to go to those who restrain virus growing with medicaments,this is, and virus itself also should go acclimatization is able to live. For example flu virus, be in every year produce mutation, because this should make a new vaccine every year,undertake vaccinate. The bacteria also can happen mutation. Use penicillin treats period of time, the bacterium arose to be able to bear or endure to penicillin medicine, this is the result that the bacteria produced to mutate. Second liver virus also is such, use thing of bane of a kind of disease-resistant for long, virus can produce mutation, make its happened to be able to bear or endure to this kind of medicaments medicine. Once virus is right,a kind of medicaments is able to bear or endure after medicine, can choose other remedy to continue to treat again. Although resist the medicaments sort of second liver virus at present less, but very quickly can more new pharmaceuticals appear on the market gradually. If be treated actively, make virus is restrained very quickly, liver cell is necrotic stop, liver function improves, prevented the progress that liver fiber changes, won time to be treated further or await more effective remedy to appear. Want to be able to be used " weapon " we are in 　 when attacking the enemy, if the weapon is very much very good, enough destroys the enemy, we are OK of course machine gun, artillery shell go up together, destroy the enemy thoroughly. But if our weapon is very few, cannot make the enemy again run, we save a weapon with respect to need, diversionary live the enemy, use machine gun first, reoccupy cannon. With second liver virus " fight " also be same. Medicaments of present virus of the liver that fight second is very few still, if we no matter " opportunity for combat " , without giving thought to " weapon " , husband of interferon, rummy goes up together surely, even plus Wei of the name of a river in Shaanxi and Henan provinces of former times of A candy adenosine, extensive of what, although temporarily " the enemy " shrank first, but when the enemy " changed face " , to these " weapon " arose to be able to bear or endure property of a medicine, we but with respect to can find no way out. Still have, used so much " weapon " , in case produced side effect " injury " oneself, that can be compensate really the madam is folded again arms. So, in recent years most expert thinks the disease-resistant poison of second liver treats medicaments to should not combine application blindly, and the order follow in a continuous line that another kind of medicaments changes again after should using content of bane of a kind of disease-resistant to use period of time treats a method, but change the optimal opportunity of medicaments and breed still are in research. Not right " the enemy " loosen " vigilant " after 　 is using disease-resistant bane thing, because liver function is normal,do not want, DNA of second liver virus turns shade, we are right also " the enemy " loosen " vigilant " . Because current medicaments is returned,cannot keep clear of second liver virus completely, although virus was restrained, but these " the enemy " still be inside body, they produce mutation possibly at any time, undertake sabotage to liver again. Accordingly, using disease-resistant bane thing after remedial period occasional achieves curative effect to stop drug, answer to check to the hospital regularly, monitor " the enemy " " tendercy " . Once discovery is unusual, seasonable cure. Want and " the enemy " hit " protracted battle " because 　 is current the effect that medicaments of virus of the liver that fight second can have to restrain virus only, because this is current,the remedial method of the praise highly on international undertakes administrative for a long time to chronic hepatitis B namely. In other words, hit with second liver virus namely " protracted battle " . Half-life of general disease-resistant bane content is ten hours, half-life of lasting effect interferon can achieve 4 ～ 5 days, because this wants to use drug everyday according to the half-life of medicaments, or use drug every week. Cannot take drug today, leakage will take; to perhaps want to be treated tomorrow, forgot to just also cannot achieve initial curative effect to stop drug with respect to; stopping drug. Such cure removes the inhibition that is less than pair of second liver virus not only, and be able to bear or endure possibly still quickly medical happening. Want to hold to abiding cure, make second liver virus is in for a long time control a state, achieve HBV DNA shade finally to turn, liver function restores, e antigen shade turns, appear the virus of E antibody " hibernant " state, make liver cell gets protective. The cure of hepatitis B has appeared " dawn " , a few medicaments can have controlled an illness, a few medicaments are studying and develop. But rely on these disease-resistant bane content to make only " weapon " , not exquisite " strategic tactics " the ground blind " hit " , do not have conquer very likely " the enemy " , instead hurt him. What the 432 second liver that treats about second liver fights virus is classical 5 ask (the exercitation edits: Plum apricot)