What drug should poison of second liver disease-resistant choose?

　 of normal bane of second liver disease-resistant ends 2007, win the approval of our country and American food and medicaments management board, the medicaments that with Yu Yi liver disease-resistant poison treats has two kinds big only: Interferon kind with nucleotide kind. Interferon has two kinds, one kind is common interferon, additionally one kind is to get together glycol interferon (trade name: Clique collect glad, admire is happy can) ; nucleotide kind medicine has 4 kinds, include rummy husband to decide (trade name: He Puding) , Adefuwei (trade name: Congratulate dimension force, Dai Ding, name) , favour for Ka Wei (trade name: Rich road decides) and for decide than the husband (trade name: Element compares volt) . Two kinds of medicaments, each have interferon of actor defect 　 and nucleotide kind medicaments has the effect that restrains second liver virus, and interferon still is immune conditioning agent at the same time, have immune adjustment and direct disease-resistant poisonous effect. Nucleotide kind the active that medicaments restrains virus to duplicate is very strong, can restrain second liver virus very quickly to duplicate, and effective to great majority patient. Want a drug only everyday, very convenient, have undesirable reaction rarely. However, nucleotide kind medicaments is right " big 3 this world " action is very slow, curative effect is not stable, need to take drug for a long time, cannot stop drug at will. Want to had used this kind of drug, must comply with strictly the doctor's guidance. At faze element remedial time is 6 ～ 12 months, the index of curative effect is: Cleared " big 3 this world " ; serum transaminase is normal check of; serum virus does not come out. Interferon achieves curative effect through invoking immune power of the patient, the curative effect after stopping drug is quite stable. Because interferon must pass immunity to arouse,achieving curative effect, the reaction of everybody is very so different, a period of treatment can achieve 3 curative effect to make an appointment with patient of half the number of index only entirely, although a period of treatment also has reoccupy only 70% ～ the curative effect of 80% . In addition, with interferon cure has many undesirable reaction, but should make an inspection by the regulation only, it is safe likewise. The situation of patient of every chronic second liver is different, the demand is diverse, because this cannot say which kinds of medicaments is better absolutely. Must press illness and individual other condition, the some that from the characteristic of each medicaments the choice suits relatively is planted. In the patient that examines in me, a few people already had the knowledge that comparative to second liver, have truer attitude to disease and cure, can hold to disease-resistant poison tenaciously to treat; some patients economy is not bounteous, but if can candid ground and doctor are discussed, also can explore a remedial plan that fits oneself. Chronic hepatitis B needs longer treatment, still compare hardship sometimes. Him patient must understand his disease, ability not by misdirect, ability chooses treatment according to his condition and desire, ability cooperates in doctors and patients in play subjective activity. You should choose nucleotide of 　 of which kinds of medicine kind the medicaments property of medicaments and interferon is different, remedial reaction is different also. The patient should spend bit of time to clear up both difference first. Leave a decision again not late also. If you are in senile patient, have diabetic or hypertensive old person especially, the likelihood chooses nucleotide kind medicine is safer and effective. Cure is diabetic the medicine with hypertension is to want to be taken for a long time, the nucleotide that increases a kind to also want to be taken for a long time again kind medicine, believe you can be accepted. If you are a youth, not quite recipient take drug for a long time, had not given birth to the child's young men and women especially, because fight virus medicaments to had not made embryo send the clinical trial of abnormal, during taking drug cannot be fertilized and be pregnant, of course with short-term the interferon treatment that can stop drug is better. If you have other disease at the same time, if oneself avoids hyperfunction of epidemic disease, thyroid function or function low, not pilot is diabetic, not pilot hypertension, epilepsy, these diseases are the no-no card of interferon, dan Kean applies nucleotide effectively kind medicaments, rarely medicaments conflicts. It is chronic hepatitis B together, the illness differs to also should choose somewhat. If serious liver is ill: The icteric, ascites of not easy subsidise, hematic convention examination shows leucocyte or plaque are very low, cannot use interferon, dan Kean applies nucleotide completely kind medicaments. Just, can great majority use interferon, usable also nucleotide already kind does the patient of medicaments want how to choose? If interferon cure can achieve curative effect, it is better with interferon of course, reason is: Can stop drug, curative effect is stabler, can keep clear of more quickly " big 3 this world " , after stopping drug have even inside a few years cleared " small 3 this world " hope. But the patient that is not an useful interferon can be achieved. And nucleotide kind however great majority can obtain medicaments should maintain curative effect. Accordingly, the wardmate with active demand can choose interferon; to ask reliable wardmate can choose nucleotide kind medicaments. The experience that poisonous to the disease-resistant of chronic hepatitis B cure accumulated a lot of doctors to abound, have oneself opinion. The opinion of my individual is above, and still can amend ceaselessly in the following clinical work, offer broad wardmate to consult only, everybody still basically wants to discuss with local doctor. (responsibility edits: King sea E)