What person does not need disease-resistant poison to treat?

New promulgate " guideline " middle finger goes out, whether to want to undertake disease-resistant poison is treated, must consider integratedly " HBV DNA " , " liver function " , " liver histology is checked (namely hepatic puncture is checked) " the result of these 3 examinations. 　 the 1st -- HBV DNA: "Big 3 this world " virus DNA amount of the patient obtains 105 copies / milliliter, "Small 3 this world " virus DNA amount of the patient obtains 104 copies, milliliter, this numerical value is the basis with second liver duplicate and active virus. 　 the 2nd -- liver function: Transaminase prep above is worth upper limit normally 2 times (the person that use interferon is treated has requirement) additionally, this moment is the best opportunity that has fighting virus remedial, otherwise not only curative effect not beautiful, do bad meeting generation to be able to bear or endure bounce of medicine, illness, cause serious illness hepatitis. 　 the 3rd -- liver histology examination: Although transaminase is less than upper limit of 2 times normal value, but discovery of liver histology result, liver fiber changes index to already exceeded mark to be fastened to certain level, or inflammation is necrotic heavier. 　 folk prescription, health care is tasted and use blindly fall enzymatic medicaments, it is the typical error that second liver patient uses drug. Although they used many remedy, but did not use to drop however, of rejection of the most important disease-resistant bane content aside. Gao Zhiliang (Zhongshan university is accessary science and education of catch a disease of feeling of the 3rd hospital is awarded) if having a word and Zhuang Hui academician different in approach but equally satisfactory in result -- " disease-resistant poison, fall best namely enzymatic medicine. " 　 of 　 　 　 " Right deviation abandons principle " be a mistake, but " creed of left rash advance " be a mistake likewise, the patient that ought not to have fighting virus remedial more very much however " ought not to move in disorder " . Professor Gao Zhiliang is very anxious to this: "A lot of physicians encounter second liver patient, no matter whether its accord with disease-resistant poison to point to,ask for, none hesitant go up rummy husband is decided or Adefuwei () of disease-resistant bane content, actually this is incorrect, such doing give an issue probably. " a lot of doctors point to cure proof expand innocently of purpose, the person that bring about what do not need to refuse ill poisonous treatment more very much to carry makes a patient between one night, in joining the range that treats main forces hurriedly, go. 　 3 in, the 1st is essential condition. In accord with L below premise, have the 2nd again or the 3rd, accord with those who fight virus to point to asked for. 　 from afore-mentioned pointing to that it is OK to ask for us see, the standard that whether the decision needs to refuse ill poisonous treatment is not think like Everyman in that way, "Big 3 this world " be about to fight virus, "Small 3 this world " need not fight virus. In fact, "Big 3 this world " the person that carry, if liver function is normal, and liver histology examination shows inflammation is lighter, beardless disease-resistant is poisonous. And " small 3 this world " person if DNA is electropositive (accord with L namely) , and transaminase unusual or indication inflammation of liver histology examination is more serious, need to undertake disease-resistant poison is treated. Some people can say the possibility: "Satisfied the 2nd to go, transaminase is elevatory, do not mean hepatitis activity, can you fight virus to treat thereby? " these people know only firstly, do not know secondly. The reason with elevatory transaminase is varied, can be the be caused by such as alcohol liver, overworked, medicaments, so L indispensable. This also explains remedial target basically is to make virus DNA amount drops, the exterior antigen that is not pursuit of most patient place turns shade. Virus DNA should turn to use detect commonly the method does not detect. The person that our country has second liver virus to carry is made an appointment with 120 million, generally speaking, want antigen of surface of second liver virus to be masculine gender only, liver function keeps for a long time normal, call second liver the person that virus is carried. A lot of patients, the viewpoint of not little even doctor is: The person that second liver virus is carried need not be treated. But this " guideline " point out however: The circumstance of this 100 million much person each are not identical, whether to need treatment, should distinguish treat. 　 to solve this one a Gordian knot correctly, the person that virus of liver of medical admiral second is carried is divisional the person that the person that carry for virus of chronic second liver and antigen of surface of virus of liver of second of blame activity sex are carried two kinds big. Each have two kinds of big crowds to answer measure scientificly. 　 　 1. The person that chronic HBV carries: DNA of virus of liver pointing to second is electropositive, but follow continuously inside a year visit above 3 times, the person that liver function all is carried in the second liver virus of normal limits. To this part person, best can make liver puncture inspection, so that farther diagnose is mixed,have corresponding treatment. If liver wears a result to show the inflammation inside liver organization is not active, liver fiber changes rate low, can of short duration is not treated, undertake medicine observes, check regularly if; shows the inflammation inside liver is active as a result, liver fiber changes rate taller, need to undertake disease-resistant poison reachs the fiber that fight liver to turn treatment. If did not do liver to wear an examination, also of short duration does not have treatment. 　 　 2. Be not the person that antigen of surface of virus of liver of mobile sex second carries: Show negative of antigen of E of virus of liver of positive of serum surface antigen, second, HBV DNA does not detect FPCR law) or detect under lowest be restricted, follow continuously inside a year visit above 3 times, liver function all is in the carry person of normal limits. This crowd need not have any treatment, but also need to be followed regularly visit check. (responsibility edits: King sea E)