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Monday, 23 April 2007

The liver that fight second suffers a dot do not matter

Current, poison of normal second liver disease-resistant treats medicaments, only two is plant -- interferon and nucleotide analogue, both each have actor drawback. The patient's situation is different, the choice of medicaments is different also, if young, near future has birth demand, and the person that the hope ends cure inside shorter time, can consider interferon treatment above all. Use interferon is treated, curative effect is lasting, be in " big 3 this world " in patient of chronic second liver, occurence rate of HbeAg serum changeover is higher; and, more the opportunity that hopeful gains the surface to antigen keeps clear of and be changed. Nevertheless, if choose interferon treatment, the doctor can tell a patient: "You should suffer a dot possibly " . Because, no matter use common interferon or lasting effect interferon (be like: Get together glycol changes interferon α - 2a) , 90% right-and-left patients can appear harmful response, this and its action mechanism (can adjust airframe immunity) about. "Cold " , need not handling the harmful response with the commonnest   more is kind of flu symptom, occurence rate is 70% ~ 80% . The patient is injecting 24 hours after the 1st needle normally inside, appear calorific, temperature can amount to 38 ~ 39 Celsius, but exceed 40 Celsius rarely, can accompany have have a headache, muscle ache, articulatory ache, lack of power etc. If do not exceed 38 Celsius, doctor proposal patient waters more and rest when; should exceed 38 Celsius or the patient feels afflictive, give a few solution hot demulcent drug, be like Le Song or 100 take clever, can eat first. Over- one week later when the 2nd needle, the symptom is reduced somewhat normally, and when hit the 3rd needle when, the symptom disappears basically. Investigator thinks, this is interferon brought what system of human body immunity participates in second liver virus into play actually " battle " hind, a few symptoms that the body reacts intense place is caused, reason need not notice overly. Medullary " restrain " , not be to answer thing   leucocyte or plaque to decrease then more also see, in the head normally 8 weeks appear, also some meetings end to cure continuously. Most patient does not have self-conscious symptom, the small number of people is haemorrhage of meeting occurrence gum, giddy, lack of power wait for a symptom. Accordingly, regular examination is very important, when before be being hit especially two needles, should check hematic convention and liver function. A lot of people feel fear, think this and the marrow that change cure to cause are restrained similar, actually otherwise. Interferon is done not have certain the cellular noxiousness of the medicine that change cure, amount of this kind of leucocyte decreases cross a gender. Of course, if the neuter bead cell in leucocyte is absolutely,computation rises less at 1 × 10(9) / , or plaque rises less at 50 × 10(9) / , the doctor can make corresponding processing, if use litre of leucocyte drug, adjust interferon dosage to stop drug even. Reason patient need not be in a state of anxiety, should observe closely only can. Trichomadesis is false appearance, lose one's hair of more important   is treating the mood normally later period appears. Some patients, especially girl, mind this very much. Actually, if change the lose one's hair of cure be caused by,this is not, is the hair falls off only relatively at ordinary times a bit much just, discover when shampoo or do up one's hair more, the patient can be at ease, trichomadesis phenomenon is temporary, also won't appear bald. Nevertheless, wanting those who warn a family member is, should pay close attention to the patient's mood. Interferon can cause mind unusual, although occurence rate is extremely low, but the patient is appearing when the symptom such as depressed, covet, angst, oneself is not aware of certainly. So, the consideration of family is very serious, answer to maintain good communication with the doctor. Patient and doctor resemble athlete and coach, be in cure card of this gold nugget to capture and try hard, meantime hard to avoid should be paid " blood and sweat " , but should believe to be met sooner or later after suffering comes happiness. In interferon cure obtains E antigen to turn after shade, its recrudesce probability is small, maintain curative effect time to grow; to occupy data story, use get together glycol changes interferon α - 2a cure stops drug after 1 year, in following the patient that visits 4 years, exterior antigen turns the number of shade is occupied 11% . Although this proportion is not high, but offer a patient certain hope, raised remedial hope. The project   that the examination wants before cure chooses interferon treatment, the patient checks hematic convention besides need, in order to know leucocyte level outside, sift even check disease of immunity of a few oneself, wait like lupus erythematosus of Jia Kang, diabetic, rheumatoid arthritis, system, because the hurried immunity of interferon adjusts,action can cause these diseases. In the meantime, had better look for doctor of liver ill specialized subject to be opposite at present second liver illness undertakes be assessmented integratedly, it is normal in if diagnose,be that total bilirubin of terminal liver cirrhosis, heavy-duty hepatitis or serum exceeds value upper limit 2 times above, do not suit to use interferon to treat. (the exercitation edits: Plum apricot)

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