Are 6 kinds of medicaments had absolutely " big wrist " ?

At present the medicaments of the accepted and effective has appeared on the market remedial second liver inside our country and whole world limits includes interferon and nucleotide analogue two kinds big, they are common interferon respectively α , get together husband of α , rummy decides glycol interferon, ester, favour replaces Adefuwei Ka Wei and for add up to surely than the husband content of bane of 6 kinds of disease-resistant. Nucleotide analogue is in recent years new drug, include rummy husband to decide, ester of A Defu Wei and favour replace calorie of Wei San to plant. Its advantage is profess to convinced uses drug, very convenient; is additional suitable scope is very wide, besides use at chronic hepatitis, still can use at patient of cirrhosis of heavy-duty hepatitis and activity liver, and these two kinds of patients are to cannot use interferon. Interferon advantage depends on can be being used at patient of children second liver, period of treatment is relatively short, once cure is obtained respondent, hold time is longer, recrudescent probability is lesser. The integrated consideration of the long-term sex that treats in view of disease-resistant poison, effectiveness and security, first selection is recommended to get together commonly when cure ester of α , A Defu Wei or favour replace glycol interferon Ka Wei, second choose common interferon husband of α , rummy is decided, for decide than the husband. Why to want first selection to get together do ester of α , A Defu Wei or favour replace glycol interferon block Wei? Main reason is above poisonous curative effect of disease-resistant of 3 kinds of medicine is better, can use for a long time, during using drug, mix the variation of late unripe virus that uses drug is able to bear or endure medical phenomenon is less. Second choose common interferon husband of α , rummy decides, replacing the main reason that decides than the husband is: 1, α curative effect is inferior to common interferon get together glycol interferon α , it is common interferon again α is treated inferior curative effect of patient of liver of second of descendants ethnic group is poorer, if choose common interferon,α is treated inferior patient of descendants second liver, effective and respondent rate has 20% to control only, and use get together glycol interferon α , businesslike can rise 50% the left and right sides. 2, second choosing rummy to the husband decides and replace the matter that decides than the husband is: 2 medicine have higher virus mutation probability to happen, rummy husband is the 1st year surely 14% , replace the 4th year for 66%; be being decided than the husband is the new nucleotide that just appears on the market kind new drug, the result that its fight virus is right, excel rummy husband is decided, the probability that produces ill poisonous mutation also should be less than rummy husband to decide, but produce mutation to be able to bear or endure medical probability still De Fuwei of prep above A and favour replace Ka Wei, should arrive with respect to great influence the use foreground of this medicine. Does first selection get together do ester of α , A Defu Wei or favour replace glycol interferon block Wei Youmo difference? Get together generally speaking glycol interferon α period of treatment is relatively a few shorter, come 1 year for 6 months commonly time, agree with the age is lesser person, if children, teenager, youth is used, period of treatment is short, to wanting the person that marry to bear, relatively recipient. Get together α cannot use glycol interferon at liver cirrhosis to lose acting countervail patient, also cannot use at appearing icteric second liver patient, the price slants expensive, the conference between operating period appears to cross sexual marrow restrain reach the harmful response such as kind of cold, these problems restricted this to be used extensively of medicine. Ester of A Defu Wei and favour basically are used at adult second liver to treat for Ka Wei, cannot use at cure of children second liver temporarily, these 2 medicine are used rise relative safety, the body in treating a process is done not have apparently unwell, control virus rate faster, turn in the light of shade of DNA of second liver virus especially, curative effect is distinct, but antigen of E of virus of occurrence second liver and E antibody are serological changeover is relatively difficult, it is OK to treat shade of ill DNA of liver of the second after a year to turn achieve 60% above, but antigen of E of virus of occurrence second liver and E antibody are serological the probability of changeover has 20% to control only, this asks 2 kinds of medicaments are used for a long time, remedial terminus must see antigen of E of second liver virus and E antibody are serological changeover, to the second liver of negative of antigen of E of second liver virus, remedial terminus is antigen of surface of second liver virus turns shade, come so, time need of cure is quite endless. Virus mutation appears to be able to bear or endure during ester of A Defu Wei and favour replace Ka Wei to use medical circumstance is close friends Yulamifu is decided and replace decide than the husband, after Adefuwei uses 2 years, occurrence virus mutation is able to bear or endure medical probability is 3% the left and right sides, favour be less than for Ka Wei 1% , this is the advantage place of these 2 kinds of medicaments, but remedial terminus is very distant, be destined 2 medicine use need to perserve use. Result of meeting occurrence kidney damages the patient that seldom counts use Adefuwei, must change medicine right now. As a result of every patient condition differs, when the clinician is making remedial plan, the metropolis is discreet balance, undertake individual influence a choice, nonexistent which medicine is good, the problem with which bad medicine. Use interferon disease-resistant is poisonous, should master strictly get used to disease, the patient such as disease of immunity of low, oneself cannot use serious liver cirrhosis, epileptic, invigorative medical history, leucocyte and plaque. In using drug, want to monitor blood picture, transaminase, virus closely to learn index and blood sugar, thyroid function to wait, avoid to appear serious side effect. Use nucleotide kind in medicaments process, also want to notice liver function and the virus such as the transaminase that monitor learn index. (the exercitation edits: Plum apricot)