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Monday, 27 August 2007

Is second liver treated hard difficult in where?

At present method of the most effective second liver treatment is disease-resistant poison, immunity adjustment, it is improvement liver function and prevent liver cirrhosis, is not to go after virus shade to turn painstakingly. Many second liver patients, many time and money were spent on cure, but curative effect is not apparent; so far, although the medicaments that application treats at liver disease and therapeutics are very much, but the effect is goodish however, is this why? Taking heavy question, the reporter visited ill hospital of liver of Heibei traditional Chinese medical science to bright Dean Lan Shu. The objective reason   that second liver treats hard has the brighting dean of more than 40 years of clinical experience to no matter the doctor of traditional Chinese medicine still is Western medicine,think, main purpose of cure should be: 1. Abiding restrain or cleared virus, make hepatitis pathological changes alleviates, prevent the happening of liver cirrhosis and even liver cancer. 2. Reduce or eliminate infectivity, prevent liverish to spread namely. The main reason that second liver treats hard has the following sides: ① virus is in existence more. Second liver virus is virus of sex of extensive be addicted to, can be in hepatic, bile duct exists in organization and the cell such as epithelial, pancreatic, lymphocyte and duplicate. Disease-resistant bane content keeps clear of more easily the) of virus of HBV(second liver in blood, and the HBV in organizing a cell is kept clear of not easily or keep clear of later, make main reason of recrudesce. ② immunity is able to bear or endure suffer. Perpendicular transmission and infant level transmission are Mu Ying the main infection characteristic of our country HBV. Growth of airframe immunity system and HBV infection, duplicate photograph is accompanied, after waiting for immune system to mature, can consider as HBV oneself composition by accident and produce repellent and cleared reaction hard. This is liver of our country chronic second refractory is important reason. ③ gene is integrated. After virus of liver of the second on inchoate infection, because immunity is able to bear or endure,suffer, often do not have semiotic expression, when coming to manhood period discovers and begin therapy, among often removed already more than 10 years, ribonucleic acid of to oxigenate of second liver virus produced conformity of much place gene already. Treat right now, although serum is medium second liver virus is multinomial index, be like two half-and-half medium E antigen drop or disappear, the integrated virus gene inside the cell still can duplicate after stopping drug, expression, cause bounce, recrudesce. This is the another main reason that causes second liver to be treated hard. ④ gene mutates. Think on the tradition, virus turns shade (be like big 3 this world turn for small 3 this world ) it is virus duplicate and abate, infectivity is reduced, the mark that the illness improves. But newest research makes clear, although big 3 this world turn for small 3 this world , want ribonucleic acid of to oxigenate of second liver virus only (HBV-DNA) is masculine gender, likely and adumbrative second liver virus already produced mutation. This kind of mutation explains, virus still duplicates active, still infectious. And E antigen (HBeAg) cannot be conveyed, state virus is kept clear of not easily, send easily change development chronically. More of flooey is, treatment of virus of antagonism of individual plant of this kind of mutation is not sensitive, expression leads tall, long-dated curative effect to have a relapse not beautiful. What the place of above of subjective element   that second liver governs hard tells basically is a few objective elements that chronic second liver controls hard, additionally still not little subjective element affected curative effect greatly. Be like: ① object choice is improper. The limits that a lot of patients do not belong to disease-resistant poison to treat (if chronic is poisonous the person that carry, medium the) such as terminal liver cirrhosis patient, extortionary however use interferon is treated, not only obtain curative effect hard, cause undesirable reaction easily instead. ② uses formulary record incorrect. Although a few patients belong to the limits that refuses ill poisonous treatment, but chooses disease-resistant poison treats medicaments and dosage, period of treatment incorrect however, clinical go up also hard be successful. For example, patient of liver of our country second to α - the right dosage of interferon should is 5 million to 10 million unit, period of treatment comes 1 year for half an year, but very rare however patient insists to undertake according to this. ③ is abused and use remedy in disorder. Some patients demand medical service everywhere, use Western medicine today, will use Chinese traditional medicine tomorrow, plus the advertisement with various items, more let their not know what to do. The result that abuses medicaments can increase hepatic burden only, delayed an illness, increased remedial difficulty even aggravate the illness is exasperate. Method of proper treatment liverish Dean   brighting sums up finally induced answer of proper treatment liverish: Cooperate doctor cure, notice a few contraindication, disease of liver of relaxed and hopeful = recovers. He advocates remedial liverish meaning is: 1. Restrain virus to duplicate, stimulative virus is cleared. 2. Relieve hepatic inflammation, improve hepatic organization, rehabilitate of stimulative liver cell. 3. Prevent or defer liver cirrhosis. 4. Lower the occurence rate of HBV dependency liver cancer. 5. Improve life quality of the patient, lengthen a patient live period. 6. Defer, remove clinical symptom of the patient. He thinks at present method of the most effective second liver treatment is disease-resistant poison, immunity adjustment, it is improvement liver function and prevent liver cirrhosis, is not to go after virus shade to turn painstakingly. (the exercitation edits: Plum apricot)

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