Tuesday, 14 August 2007
The liver that treat second is answered " person " with medicine
According to the different genotype of second liver virus, the remedial effect that uses interferon and nucleotide analogue also can differ somewhat. Chronic second liver is in China incidence of a disease is very high, make an appointment with according to estimating to have in the crowd very one of, namely 120 million, it is positive of antigen of second liver surface person; is made an appointment with among them 1/4, namely 30 million for patient of chronic second liver. These patients need to undertake disease-resistant poison is treated, restrain second liver virus for a long time thereby, prevent and defer second liver disease to make progress liver cirrhosis liver cancer. The expert expresses, although at present second liver is cured completely very hard, but bane of existing two kinds of big disease-resistant, interferon and nucleotide analogue, control the disease effectively, if restrain second liver virus to arrive lowermost level and even do not detect in blood, realize E antigen turn shade or serum changeover (big 3 this world turn for small 3 in relief) , transaminase returns to normal etc. Hold to long-term and normal disease-resistant poison to treat, check regularly, the illness can gain very good control, the patient can work normally and learn. According to the different genotype of second liver virus, the remedial effect that uses interferon and nucleotide analogue also can differ somewhat. Genotype of the A in Caucasian and D genotype are more, and person of the yellow race especially in patient of Chinese second liver, great majority is B genotype and C genotype. A with D model effect of therapy of patient use interferon is close friends at B model with C model. Division of infection of Guangzhou southern hospital Professor Hou Professor Jin Lin reported analogue replaces a kind of new-style nucleotide that is used at treating chronic hepatitis B to be decided than the husband (element compares volt) undertake technically in Chinese patient 3 period clinical trial result of 2 years. The result shows, for use drug 2 years surely than the husband, have very strong virus inhibition. In Chinese patient E antigen turns shade rate is very high also, amount to 40% , serum changeover rate is amounted to 29% . (the exercitation edits: Plum apricot)
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