Complementary powerful powerful combination treats Chinese and Western second liver

Well-known, because human body contracted hepatitis B virus,hepatitis B is (HBV) hind what cause. According to story of foreign medicine magazine, current, the person that the whole world has second liver to affect about 350 million person, our country occupied among them 1/3 about (namely 120 million person) , the face has 10 ％ to be patient of chronic second liver here, and the person that there are 4 ％ about in patient of chronic second liver can develop liver cirrhosis or liver cancer finally. Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 tastes alternate newly to go out drive market enlarge to allow Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 to occupy estimation of domestic medicine expert, the total cost that our country uses every year at treating second liver is controlled in 100 billion yuan of RMBs at least, what kind of this one market is tremendous it is thus clear that. As a result of second liver virus (HBV) be one kind " virus of sex of liver of be addicted to " , it duplicates technically inside liver cell, and hepatic itself all has catabolism to any medicaments, cure of reason second liver also is one of the world's accepted medical treatment difficult problem. As the flying development of medical science and technology, came 10 years in the past, second liver treated agent development to obtain significant progress, especially a series of nucleotide kind fight HBV new drug, if rummy husband is decided, ester of A Defu Wei, favour replaces calorie of Wei He to be decided for Mi Fu with what period of as soon as possible appears on the market is protein kind of medicaments (like interferon, Bai Jiesu - 18 wait for a product, for second liver cure provided powerful technical support. Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 is current, liver of clinical cure second basically uses international medicine group nucleotide kind medicine and interferon. And our country is clinical remedy of use the liver that fight second basically can be divided it is 3 kinds big, namely interferon kind, nucleotide kind with Chinese traditional medicine kind, can saying is " Chinese and Western is united in wedlock, each shows special prowess " , have the power of mutual complement. This also is the one big characteristic of market of our country medicine. Nucleotide kind progress is the rapiddest Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 fights second liver medicaments and character, at present domestic and international market basically is controlled by place of company of the famous pharmacy that cross a state. First nucleotide that Shi Ke of arrowroot orchid element develops kind medicaments rummy husband is decided (trade name is " He Puding " ) after appearing on the market (domestic product shows to be produced by company of element of Suzhou Ge Lan) , ever held the vantage ground that defies hepatitis pharmaceuticals market for a time. Should taste especially marched formally 1999 after our country, because can make effectively,antigen of surface of second liver virus turns shade, the fast after reason appears on the market is crash for domestic hospital commonly used second liver is clinical the breed that use drug, sales volume criterion from 2000 100 million multivariate rise it is 550 million yuan of 2005 (somebody estimates, total sales of congratulate general fourth home already exceeded 600 million yuan last year) . Because price of congratulate general tinkle is opposite taller (every price is 17 yuan) , what at present main market of He Puding centers reason in economy of our country the eastpart part to develop is big in in the city, and owe the center-west region sales volume that develop relatively in economy very low. 　 of Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 in May 2005, another transnational corporation 100 when the favour of new drug of the liver that fight second of beautiful Shi Guibao replaces Ka Wei (trade name is " rich road is decided " ) the press conference before appearing on the market was held in Guangzhou city. According to large and clinical research the report makes clear, favour the Wei Tong that replace card belongs to nucleotide kind medicine, but its disease-resistant poisonous ability is greater, side effect is less, and be able to bear or endure medical rate is current ongoing with the nucleotide that appear on the market kind of the lowest in medicine. Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 is caught, company of arrowroot orchid element the new drug of the liver that fight second that immediately announces to its are developed ester of A Defu Wei (trade name is " He Wei force " ) appear on the market in the round in China, this action sees Ge Lan fine of intention of element history gram is bitter: Graph of one party interview is replaced with its be able to bear or endure the rummy husband with bigger property of a medicine is decided; On the other hand, also alleviate favour be about to be in for Ka Wei China appear on the market brought wallop. 　 of Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 in November 2005, bureau of Chinese medicine inspect approves rich road formally to appear on the market in home surely sale. From the point of the circumstance that at present the market feedbacks, afore-mentioned two kinds new-style medicaments of the liver that fight second (namely He Wei force and rich road are decided) odd assortment sale already all exceeded 100 million yuan of RMB, go sign is good. Nuo of Beijing of another joint-stock company China also supervised management board to refer new drug of the liver that fight second to replace to national provision medicines and chemical reagents in Feburary 2006 decide than the husband (it is nucleotide together kind) register application document. This medicine already finished Ⅲ period in China clinical trial, and hopeful is in first half of the year this year China appear on the market. Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 occupies the introduction, favour the Wei that replace card, for the clinical curative effect that decides than the husband all excel rummy husband is decided, the newest research data that the European liver disease that just will end April from this year publishs on annual meeting looks, with Adefuwei ester photograph is compared, favour fall for what block Wei virus capability is faster, stronger. Come early treat the 10th day, favour the statistical difference with the extent that replaces calorie of Wei Jiang virus to hold an amount and more notable than having photograph of ester of A Defu Wei; When treating 48 weeks, the patient virus that 58 ％ favour treats for Ka Wei carries a quantity to drop to cannot detect level, and ester of A Defu Wei contrasts group for 19% . In the meantime, of content of existing bane of second liver disease-resistant be able to bear or endure medical data shows, different remedy is used in the patient is treated at the beginning of nucleotide, be able to bear or endure in what treat the 4th year medical occurence rate is respectively: Rummy husband is 71 ％ surely, ester of A Defu Wei is 18 ％ , favour for Ka Wei under 1 ％ . Vaccine of liver of second of Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 nods Cheng Xinliang Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 to be in respect of other treatment medicaments, 21% what the Luo Xin of Pai of preparation of lasting effect interferon that produces by company of collect family name held share of market of second liver pharmaceuticals all the time in our country, its develop latent capacity to not allow to ignore, but because its price is higher, affected the market of partial area to sell. After Nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 　 enters 21 centuries, second liver vaccine is become new rise another second liver treats an agent (tell on firm sense, second liver vaccine can be curative of immune medicaments and rather than only. But from statistical angle criterion medicaments of liver of its classify second kind) . The vaccine of gene second liver that at present our country manufactures basically has 2 kinds: One kind is the liver of second of yeasty gene project that from American silent Sha Dong company introduces vaccinal, home has a few product line, year productivity is total amount to 100 million above (actual output is done not have so much, have 80 million ~9000 only at most 10 thousand) ; Another kind is 1991 the CHO second liver that develops independently by Chinese precaution academy of medical sciences is vaccinal, highest when produce per year 10 million, at present estimation has 6 million ~700 only 10 thousand (basically be to face the intense competition that comes from company of domestic other production) ; The second liver that installs plus the cent after Shanghai is imported from the United States directly is vaccinal, reckon at present home produces per year gross of second liver vaccine to fluctuate in 150 million. Total sales of market of second liver vaccine is 1 billion ~15 about 100 million yuan of RMBs (because the factory price of second liver vaccine differs,this is great, raise 7 yuan of RMBs to differ to a few yuan 20 from every) . (the exercitation edits: Plum apricot)