Sunday, 12 August 2007
Two tactics of liver of second liver third wants to catch!
Because at present the whole world has 1 person in every 12 people,be the person that second liver or third liver virus are affected, is world hepatitis allied all over the world do 200 many countries and area initiate the name is " am I the 12nd (Am I Number 12? ) " activity, aim to appeal more people rises precautionary consciousness, the action rises, prevent hepatitis. Be opposite as our country new student carry out vaccine of liver of free and vaccinal second, antigen of surface of liver of the second in children is carried rate had drop apparently. At the same time incidence of a disease of adult second liver shows ascendant trend, the adult that exceeds half the number does not have the protection of antibody of second liver surface. Second liver treats a method at present much, continuously curative effect is poor, and although third liver compares second liver to discover harder, cure more easily however. Why does hepatic love " inflammation " Director Yuan Guiyu tells ill expert of liver of hospital of contagion of Tianjin city us, we also are ceaseless evolution to the understanding of hepatitis, at present our consensus is hepatitis virus basically is armour, second, third, fourth, the fifth of the ten Heavenly Stem 5 kinds, these 5 kinds of virus have a common characteristic, encroach our liver technically namely, also be said to do " virus of liver of be addicted to " , basically survive inside liver cell and duplicate, harm is hepatic. Among them armour, virus of the fifth of the ten Heavenly Stem hepatitis is infected for enteron, classics excrement and urine travels, prognostic and good, without change the trend chronically, become the risk of cancer of the liver without evolution, opposite and character harm degree is smaller. And at present armour liver has had vaccine, the vaccine of liver of the fifth of the ten Heavenly Stem also has entered clinical trial phase, can appear on the market before long. Man hepatitis virus is blemish virus, must survive inside the crust of second liver virus, do not come on basically independently. The harm is the at present greatest is second liver and third liver. The liver of thing second that second liver prevents to make vaccine is the child not only comes on in the contagion of legal report number and incidence of a disease occupy front row high all the time for years. Our country begins a second liver vaccine to label a new student from 1992 plan immunity category, all new students since 2002 since free have an inoculation, antigen of surface of liver of the second in children is carried rate already had drop apparently. At present antigen of surface of liver of second of our country crowd is carried rate dropped to make an appointment with 2.6 percent. Among them, 1-4 year old children lowest, for 0.96%; 15-59 year old the crowd still is as high as 8.57% . Han Tao of expert of internal medicine of assistant dean of 3 centers hospital, liver tells a reporter, treating second liver is very of costly, fee of patient of liver of a second of our country's at present annual diagnosis and treatment needs 20 thousand multivariate, and if making vaccine, the price also 80 multivariate arrive 200 multivariate, the vaccine of tall antigen content can provide the effective protection that is as long as 15 years. Everybody can calculate this Zhang. Second liver should be checked first before vaccinal second liver is vaccinal " two half-and-half " , normal and the person that do not have antibody carries check-up result, the hospital that prevent ill center to place or has family of precautionary health care can vaccinal. The person that did not contract second liver virus, person that virus of the liver that do not have second is carried and patient of the liver that be not second are susceptible person of second liver virus, all need to undertake vaccinate. And patient of liver of the person that obtain effective protection antibody already virus, naturally now to affecting second liver, second or the person that virus is carried is invalid, need not again vaccination. Third liver does not have vaccinal expert to recommend: Because third liver virus is RNA virus, of antibody of the liver that check third is added when examining system, mutate very easily, still do not have vaccine to be able to prevent at present. Gui Yu of contagion hospital Yuan points out, third liver is the virus that just named 1989, inchoate symptom special hide, be ignored very easily and by accident examine, the hepatic inflammation reaction that causes as a result of third liver is weak, the doctor discovers not easily, 75%-85% can turn into chronic, final development is liver cirrhosis and liver cancer. Travel besides blood, transmission of mucous membrane of third liver skin is more serious than second liver also, following crowd belongs to crowd of third liver high risk: Patient of transplanting of the medical personnel, personnel that often contacts blood, organ, often blood transfusion or the domestic member of the person that accept haemal products and third liver patient. The male homosexual, person that have drugs of the inject inside many sexes spouse, vein, answer to accept third liver sieve to check as early as possible. If fight check-up to measure,show masculine gender, answer to check liver result and nucleic acid of third liver virus again, whether to undertake disease-resistant poison is treated in order to decide. Daily life defends hepatitis measure mediumly: Director Han Zhichao points out internal medicine of liver of 3 centers hospital, second liver and third liver virus basically are passed humoral travel with blood, should exist to the likelihood " humoral or blood is exchanged " the vigilance that behavior maintains altitude. If do not want common patient of liver of second of female of; of tooth brush, razor, nail-clippers does not drop about in menses sanitary towel, conditional should burn down, or put deserted model bowl to immerse with alexipharmic fluid, briefs wants alone catharsis, the towel that washs privacy place to use wants special; anteprandial hind wash one's hands, the hand does not enter the mouth. Treating is disease-resistant poisonous method together the remedial method of liver of second of big different is a lot of more current, interferon and nucleotide analogue are two kinds of the commonnest medicaments. Zhuang Hui of academician of Chinese Academy of Engineering teachs the introduction, chronic second liver is disease of long-term progress sex, need long-term treatment, if undertake nucleotide kind the disease-resistant poison of medicaments is treated, the time that needs 2 years at least, and in fact, the patient of 88% needs longer time. In this process, mutate and be able to bear or endure medicine is bottleneck. In domain of prevention and cure of second liver virus, at present experts are able to bear or endure in virus medicine and mutation precaution respect accumulated certain experience, refuse the patient that virus treats to suiting to do, when choosing nucleotide analogue, be in as far as possible initiative disease-resistant poisonous action is chosen when treating strong, be able to bear or endure the medicaments with medical mutation low occurence rate, newest the clinical data that publish shows continuously, favour restrain virus ability, lowest to be able to bear or endure for what Ka Wei has fast, powerful effect medical occurence rate and abiding the capacity that controls virus. The data that the European liver disease this year publishs on annual meeting, use favour replaces the patient of chronic second liver that treats at the beginning of nucleotide Ka Wei 96 weeks, 79% virus carry a quantity to fall to cannot measure a level, adefuwei contrasts group only the patient virus of 50% carries a quantity to fall to cannot measure a level. The key of second liver prognosis is to should raise sex of patient comply with: Using nucleotide (acerbity) during analogue undertakes disease-resistant poison is treated, should follow the doctor's advice on time, full amount takes drug, restrain virus as far as possible in lowermost level, do not give virus the chance of stage a come back. In third liver domain, cure basically depends on interferon, nucleotide kind medicaments is invalid to third liver virus, and lasting effect interferon and Ba Weilin of benefit of content of bane of wide chart disease-resistant (virus Zun) operable, full period of treatment of course full amount (24 weeks) cure, the patient of 50%-70% can be obtained clinical cure, virus keeps clear of effectively. (the exercitation edits: Plum apricot)
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