Monday, 19 March 2007
Hold second liver to treat 13 points
Because certain problem is of commonsensible sex, but comrade-in-arms of a few newcome does not understand, the phenomenon that the question that asks a few have have final conclusion repeats on forum is more serious, arrange this article hereby, give a novice a reference, reduce at the same time edition advocate people the burden that answers a question. 1, the classification of second liver and definition hepatitis B cent are He Yalin of acute second liver, chronic second liver the bed affects 3 kinds. After major adult contracts second liver virus with inferior clinical infection process gains heal and the immune strength to second liver (healthy person has been when these people are being checked actually, typical 2 half-and-half outcome is 2, 4, 5 or 2, 5 electropositive) , fraction development is acute second liver, acute second liver is benign course commonly, most patient is OK and complete heal, gain immune strength. Patient of liver of second of few number acute and the person that travel through mother baby in great quantities or second liver virus affects when cheeper and the person that very few a few manhood are affected makes patient of chronic second liver finally. The definition of patient of chronic second liver is HBsAg lasts the person that masculine gender exceeds 6 months. In patient of chronic second liver, liver meritorious service is regular, call socially " the person that virus is carried " or " healthy carrier " , liver result is abnormal, call socially " second liver patient " . But must make clear, "The person that virus is carried " and " second liver patient " between without apparent difference, both and complete can change each other inside very short time. At the same time so called " healthy carrier " just socially a non-standard appellation, this part patient is not healthy person, however second liver patient. These patients although index of liver function assay everything is normal, liver had had more serious inflammation possibly also, cannot think liver result is healthy person normally completely oneself so, still should have done check regularly, so that discover a problem in time. 2, the cure of the liver of chronic second of current situation that chronic second liver treats still is cosmopolitan difficult problem, can effect a radical cure without specific at present second liver. American food and medicaments management board (the is used at treating chronic second liver remedy that FDA) approves, end to share 3 kinds at present, namely: α - husband of interferon, rummy is decided (trade name He Puding) , Adefuwei (this medicine has not appear on the market in China) . May effective, but the medicaments that was not approved to use at treating second liver by FDA has: Trade name day of 1(of thymus discard α amounts to celestial being) . The has remedial effect to second liver remedy that has been washed out has: Natrium of formic acid of adenosine of candy of Wei of A Xiluo Wei, the name of a river in Shaanxi and Henan provinces of extensive former times, A and its ramification, 暽 . Anyhow, the thing of main disease-resistant bane that at present home uses at treating second liver is interferon and rummy husband to decide, interferon is first selection medicine. 3, cure must be in the poison of opportunity disease-resistant that disease-resistant poison treats the effect with when liver has mobile sex inflammation, undertake just may be receivinged better. The use standard of interferon is: ALT is in 80 with 400 between, area of the C before virus is not had mutates (namely small 3 this world + HBV-DNA electropositive) , direct bilirubin is normal, indirect bilirubin is basic and normal, HBV-DNA positive. The use level that rummy husband decides is: ALTgt;80, HBV-DNA positive. If satisfy the use condition that interferon and rummy husband decide at the same time, should use interferon. Fall in a few not typical situations (if ALT is in 40 with 80 between, liver meritorious service is regular but B exceeds a result ceaseless aggravation, ALT is normal but globulin is elevatory) , the proposal undertakes liver is worn, if inflammation classifications in G2-G4, same need undertakes disease-resistant poison is treated. A bit need to emphasize, when these not typical situations happen, must liver is worn affirm ability can undertake disease-resistant poison is treated, and cannot oneself begin to use drug boldly, otherwise consequence expects hard. (The situation of everybody is different, remedial program is different, what raising a proposal is opposite, common, but not be absolutely) 4, the use principle of the medicaments that protect liver is, be not emergency commonly, do not suggest to use the remedy that protect liver. The premise that uses the remedy that protect liver is: ALTgt;400 lasts a week above, bilirubin lasts badly out of order a week above. At present the commonly used medicaments that protect liver is Ganlixin or hepatitis spirit, put after stopping drug easy rebounding problem, when stopping drug so must careful, with reducing dosage stage by stage advisable. (Attention, say here " the medicine that protect liver " show immune depressor and blame particularity fight phlogistic drug, at present the many such as on the market " protect liver piece " of and so on in into pharmacodynamics of the medicine that protect liver unidentified, psychology comforts action to be more than practical effect, should not use below any circumstances) 5, of patient of chronic second liver check regularly suggests every 3 months do patient of chronic second liver commonly liver result + 2 half-and-half (qualitative) + HBV-DNA(mensurable) , every half an year does B to exceed + ) of albumen of AFP(armour embryo, every 3 months do liver cirrhosis patient AFP, other is the same as chronic second liver patient. If the body feels unwell, need to be checked in time. If B exceeds a result to have liver thread,be changed or the evidence of liver cirrhosis, had better do liver to wear certain level. 6, about at present on the market many in officinal and so called " specific " is current and so-called what can treat second liver is medium officinal no less than 400 kinds, what have good curative effect truly among them however is very few, proposal patient to what did not mention in the article in officinal and uniform do not take. Still a bit must be make clear, at present second liver does not have specific, heal without law, so everything is publicized on the market can " cure second liver " , " make size 3 this world turn shade " medicines and chemical reagents, therapeutics, hospital is complete cheater, everybody should notice to differentiate true bogus. (Emphasize: Second liver heals without law at present! Do not believe any advertisement! ) 7, join element painstakingly to have injection about joining element painstakingly, also capsule offers profess to convinced (trade name) of glad of Boertaili, Tian Qing answer, its ensure liver result clearer, in using a process at the same time, can make the HBV-DNA level of one part patient falls, can make a few patients big even 3 turn small 3, but the condition before the level of patient serum HBV-DNA of the 99% above after stopping drug resumes treatment, so, cannot regard content of bane of a kind of disease-resistant as to use bitter ginseng element, its utility should be confined to protects liver to fall enzymatic. 8, after the of virus mutation problem that rummy husband causes surely takes rummy husband to decide 10 months continuously, the patient of 20% can produce YMDD virus mutation, continue to take rummy husband to come 4 years surely, the patient that can have 60% finally can produce YMDD mutation. After producing YMDD to mutate, level of patient serum HBV-DNA will be elevatory, but as a result of individual plant of YMDD mutation virus duplicate ability compares feral virus individual plant to lose, the level before normally so short of treats the level of DNA. On body of one part patient, as HBV-DNA elevatory what still can accompany result having liver is abnormal, in at present Adefuwei still does not have the circumstance that appears on the market in China to fall, this part patient with normal bilirubin but cure of try out interferon, the patient with abnormal bilirubin should protect liver processing in time, at the same time rummy husband must continue to take surely, if stop drug boldly, the likelihood causes feral virus to erupt, create life risk. 9, the period of treatment of the interferon of stopping drug that interferon and rummy husband decide is half an year commonly, if curative effect is bad, can lengthen, if curative effect is bad still, can stop drug. Rummy husband decides stop drug more complex. Treating feral virus trunk of a tree (namely big 3 this world or 15 this world) when, if achieve small 3 this world + DNA is electronegative + liver result holds half an year normally, can stop drug. Individual plant of virus of mutation of area of the C before be being treated (namely small 3 this world + DNA is electropositive) when, without specific standard stopping drug, think at least should take drug two years commonly DNA is electronegative at the same time and when liver meritorious service is regular, ability considers to stop medical problem. After producing YMDD to mutate, specific answer a method to be able to be referred to rummy husband decided consensus of clinical application expert 2001. 10, patient of liver of chronic second of the life of patient of chronic second liver and dietary is coming on period should assure to rest, food is delicate, prohibit sexual life. Teetotal at ordinary times, abstemious and acrimony, avoid excessive overworked can, the doctor of traditional Chinese medicine thinks " cannot eat hotpot " , " cannot eat seafood " even " cannot have meat or fish " do not have a basis more. 11, the patient of chronic second liver that the prognostic of patient of chronic second liver has 1% to be less than can be natural heal, the patient of 99% above does not have other this opportunity, any medicaments are at present helpless the scale of the heal end Yudigaoche. But the patient should notice to check only, maintain proper, life and Everyman are other without large area. Among them the most important wanted absolutely pussyfoot namely, occupy my individual to observe, have the patient of chronic second liver of drinking habit, what can have lived 50 years old is very few, so this is Chongzhongzhi is weighed. If maintain undeserved, patient of chronic second liver can produce liver fiber to change and develop the cirrhosis that it is liver finally partly, generation a series of complication, endanger life. In the meantime, still patient of cirrhosis of one part liver can produce liver cell cancer finally. This is patient of alleged and chronic hepatitis " die 3 paces music " . But must realise, should maintain only proper, check regularly, most patient can avoid this one consequence. 12, about liver result of normal the person that carry is below this kind of circumstance, the proposal does not take any medicaments, include all sorts of drug that protect liver. It is medicine 3 minutes poison, all medicaments should finish metabolization in liver, the itself that take drug also is to gave liver to increase a burden. And medicine is taken to produce effect hard when liver meritorious service is long-term and regular, will integratedly look, disadvantages outweighting the advantages. 13, the contagion that infect and prevents virus of second liver thinks to have 3 ways commonly namely (1) sex travels (include all close action that accompany humoral trade, wait like soul kiss) ( of of 2) blood transmission (3) Mu Ying transmits to be in China at present, second liver is the mainest spread everywhere to a way to travel for Mu Ying. Precautionary second liver can pass vaccine of vaccinal second liver to come true, a month after vaccinal vaccinal plan is first time have an inoculation commonly and half an year are strengthened respectively, through such program, the healthy person of 95% above can produce antibody of second liver surface, gain the immune strength of pair of second liver thereby. The one fraction person of antibody cannot produce after vaccination, having a few is the second liver virus that had contracted drop, it is common device only cannot check goes out just (this kind of circumstance can detect through the HBV-DNA of PCR obtain affirm) , these people should according to " the person that virus is carried " processing. The person of other waits for a method through increasing vaccinal dosage, can gain the immune strength of pair of second liver finally. Important remind: Interferon and rummy husband must be in next specialized subject doctor is directive use surely! Basic, the common thinkable before asking a theme is these, often can complement later. Before hope newcome friend is sending post query, can read this card carefully, not clear local reappearance invitation quizs, such not only can managing edition advocate time, also can improve the discussion quality of forum, ask everybody to cooperate, thank. Statement: The article is a forum proposal to the patient only, cannot replace hospital and doctor remedy, ask a patient to see a doctor to normal hospital. (the exercitation edits: Plum apricot)
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