Thursday, 22 March 2007
Vaccinal second liver suits a crowd vaccinally
One what is second liver vaccine vaccine of second liver is to pass gene compound antigen of second liver surface, OK and exciting airframe produces exterior antibody, have resistance to virus thereby. Vaccine of liver of gene project second is a kind of hepatitis B inferior the unit is vaccinal, the department uses contemporary live thing in the gene clone of exterior antigen is being conveyed to enter microzyme in virus of liver of technical general second, recombine Mu Jun to get HBsAg through fostering this to plant inferior unit, classics is rarefied make after the agent that add assistant is adsorptive. Nbsp; 2 why to want vaccine of vaccinal second liver what person suits to hit of second liver vaccine at present the whole world still has no the specific content that effects a radical cure second liver reachs second liver complication, exclusive and effective precautionary measures is vaccine of inject second liver. Second liver vaccine applies to all likelihoods to affect the person of second liver, key inject object is a new student partly, the children before school age, especially the new student of the person that the mother is carried for virus between gestation, another part is dangerous crowd, the medical service that includes to contact the cure of second liver virus to protect personnel; to contact blood, secretion directly protects the spouse of the person that patient of liver of personnel; second and second liver virus are carried. Domestic member or the person that contact intimately. If pregnant woman is antigen of second liver surface (HBsAg) is electropositive person, mother and new student still need globulin of immunity of inject second liver. Vaccinate is to prevent hepatitis B to reach its the of the most efficient way of serious complication and sequela 3 go making vaccine of liver of vaccinal second where, can accuse to disease precaution, hospital, community hospital goes injecting. The price of vaccine of 4 second liver offers reference only: Have two kinds. One kind is × of 5 μ G 3 / of person portion, another kind is × of 10 μ G 3 / of person portion. Dosage is different, everybody looks careful. Former in epidemic prevention branch be 12 the left and right sides, latter is 25 the left and right sides. 5 dozens of vaccine should notice what (before 1) injects must will install the vaccinal shake up inside bottle, become transparent ivory. (Allergy history and medical history ask before 2) is vaccinal, irritability constitution and the person that contract abnormal reactivity disease careful with. (3) vaccinal time: New student stitch must be in 24 hours of less than after be born are vaccinal, had jumped over earlier. If be born hind inject after 48 hours, precautionary effect is reduced. (4) is vaccinal person if have calorific, serious infection or other and serious illness, should defer vaccinal. After making vaccine, 6 have there some react normally after harmful response is vaccinal, this is the reaction of the special be caused by of vaccinal itself, the intensity that its behave follows vaccine and different. Can divide react for local reaction and whole body two kinds: 1. Local reaction. After vaccinal have an inoculation, some people can appear in pinhole place ephemeral inflammation reaction, some people can produce the inflammation reaction with red, swollen, hot, painful longitudinal in vaccinal place, some people appear possibly still local lymph node enlargement or lymphatic are phlogistic. Afore-mentioned reaction are in commonly 48-72 hour subsidise. [More] 7 what person does not suit patient of hepatitis of of vaccine of the liver that make second and contagion of calorific, acute person, serious chronic patient, the person that have the person of immune blemish, serious allergic constitution and the person that using immune depressor cannot vaccinal second liver is vaccinal. Have asthma of serum disease, bronchus, irritability nettle rash and the person that wait for a few drug allergy to penicillin, sulphanilamide is banned with. The new student that the blame such as low weight, slink, Caesarean birth is born normally, liver of temporarily unfavorable and vaccinal second is vaccinal. Although second liver vaccine is right this part new student harmless place, but because the constitutional state of its oneself is easy,produce coincidence event, because this had better postpone vaccinal time. Link: Hello, want to consult you a problem: Iridium blows Du of Jiao to whiz capture of Ψ of ∮ example Mu is unoccupied place the armpit that increase favour since? of Huang of cook of my Guo an ancient term for silk fabrics is vaccinal have profit to cure why the person that contagion hospital and epidemic prevention station reject to be carried to second liver makes vaccine... [in detail] 8 second of the period of efficacy of liver vaccine, according to formulary program have an inoculation after liver of 3 needles second is vaccinal 15 years, 51% have an inoculation person the antibody that pair of second liver virus still contain inside body, vaccination crowd still has resistance to second liver virus. For the crowd with vaccinal to vaccinal second liver proof, the immune force of crowd of half the number can maintain 15 years at least. Patient of 9 second liver (the person that carry) some people of as vaccinal as second liver confirm through assay for HBsAg positive, companion has HBeAg or fight, HBe is electropositive, the method that can adopt vaccine of inject second liver with respect to the hope at this moment makes airframe produces immune power (resistance) , kill second liver virus. But be in in fact, this kind of idea won'ts do. Above all the does not have infection sex case that the bases that we want to understand second liver vaccine is second liver virus actually (HBsAg) , return agent of some immunity assistant additionally, can help system of exciting airframe immunity produce antibody. The person that affect to second liver virus will tell, there is second liver virus inside body duplicating ceaselessly, and when virus is duplicating, the capability that synthesizes HBsAg is particularly strong, the HBsAg that contains in the second liver vaccine that because this blood is medium,HBsAg Yuan Chao of the loop passes inject is measured. So we can imagine, the so many HBsAg inside body still cannot lure the generation inside conductor to fight HBs, so additional give the HBsAg(that contained immune assistant agent again namely) of second liver vaccine, can you have much big effect again? Because this pair had affected the person of second liver virus, giving second liver vaccinal injection again is the effect that cannot have to prevent second liver apparently. But be in clinical on, second liver vaccine has fair treatment effect to chronic second liver. Be the same as second liver vaccine other disease-resistant bane operable, can make the patient HBsAg of about 30% turns shade. The second liver vaccine that the whole nation a few years ago uses generally adds polysaccharide of umbellate pore fungus to treat chronic hepatitis B to use second liver vaccine at typical case of cure namely. University of medical service of the director of institute of immunology of progress the Chinese People's Liberation Army of vaccine of 10 second liver, army teachs Wu Yuzhang 22 days to express in Beijing, below the support that plans in the science and technology such as 863 plans, he leads to study the group is developed " cure is used (synthetic peptide) hepatitis B is vaccinal " already finished Ⅰ period clinical research, beginning Ⅱ period at present clinical research. This is the first imitate antigen vaccine that has clinical trial, our country owns this vaccinal all and own intellectual property. As we have learned, this vaccine entered Ⅰ period permissibly in June 2003 clinical trial, adopt by a definite date of healthy to 52 volunteer the observation of 9 months, preliminary evidence understands this vaccinal security. Last year June, this vaccine enters Ⅱ period permissibly clinical trial, already had patient of 46 chronic hepatitis B at present using the period of treatment that use drug was completed in the test that double blind law has randomly, undertaking be followinged closely visitting observation, farther test and verify should taste the effectiveness that gets treatment of the person that try to second liver, predict to will solve blind in March in next year. (the exercitation edits: Plum apricot)
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