Tuesday, 13 March 2007
Vaccine of concerned second liver is vaccinal and classical problem
Nbsp; nbsp; one, why should make second liver vaccine? Second liver vaccine can prevent the infection of second liver virus successfully, new student liver of an unripe vaccinal second is vaccinal, can ensure basically liver of won't do second. Existing liver cirrhosis, liver cancer develops from second liver more and come, prevent second liver successfully, prevent sclerosis actually namely, prevent liver cancer stitch. Second liver vaccine is at present cheaper, every raise a few yuan of money, the people can be accepted. 2, vaccine of liver of what kind of second to choose? What use at present is much for vaccine of liver of gene project second, the vaccine of hematic source sex that uses in former days falls into disuse basically already (the reason is to have the suspicion that causes disease of hematic source sex and wasteful and many serous) . Vaccine of liver of gene project second is to use technology of contemporary gene project, compose builds those who contain gene of antigen of second liver surface to recombine plasmid, it can be used at precaution all and foregone inferior model infection of second liver virus. The vaccine of liver of gene project second that uses now recombines yeast of deoxidization ribonucleic acid for second liver vaccine and recombine vaccinal virus vaccine, dosage is every to raise 5 microgramme. 3, what is second liver uses a method correctly vaccinally? (1) if new student parents all does not have second liver, this new student answer after be born as soon as possible (inside 8 hours) give vaccine of liver of gene project second an intramuscular injection, inject place is deltoid of the upper arm (children, adult is same) , after a month, hit 1 again, 6 lunar hind hit 1 again, altogether 3 needles, this plan is called 0, 1, before children of 6 plan; and adult make vaccine, need to have laboratory test first, if 3 systems check second liver to all be negative, transaminase is normal, can press 0, 1, 6 plan undertake have an inoculation of second liver vaccine. Immunity is 90% above into power, the mark with successful immunity is antibody of second liver surface turns for masculine gender, protective time is 2 years of above commonly, vaccinal person can check regularly second liver 3 systems, want exterior antibody to still exist only, proof immunity ability as before. (The new student that 2) is positive of pure surface antigen to maternal one party, vaccine of the odd liver that use second can obtain more satisfactory result, the use method of second liver vaccine still is 0, 1, 6 plan, report thinks stitch can hit 2 (10 microgramme / L milliliter) the effect is better. (3) is antigen of surface of second liver virus and E antigen to maternal one party the new student of Shuang Yang sex had better be the globulin of second liver immunity that uses efficient price jointly and second liver vaccine. Specific means is a new student use injection 2 times globulin of immunity of liver of efficient price second (a month after be born is reached to inject each instantly after be born 1, unit of every 200 international) reach second liver vaccine 3 times (every time 10 microgramme, after be born 2, 3, each will inject 1 times in May) ; also has adopt globulin of immunity of liver of second of an efficient price injects instantly after be born, reach second liver vaccine 3 times (every time 15 microgramme, after be born, reach instantly in January, each will inject 1 times in June) , the successful rate that 2 plan protect is in 90% above. 4, how doesn't antibody arise to should do after vaccination? (Generation of antibody of 1) some people is later, be called respondent and logy. Can add to this note 1~2 needle, new perhaps vaccination, and increase dosage appropriately. (2) can be used 0, 1, 2, the immune program of 12 months. (3) is in vaccinal second liver is vaccinal at the same time, the leucocyte interpose element of operable small dose - 2. (The immunity that 4) BCG vaccine or bovine vaccine can increase pair of second liver vaccine is respondent, can cooperate to use. 5, after vaccination, does how long need again vaccinal? The antibody level of the generation after second liver vaccine is vaccinal falls gradually along with time. General vaccination, inject the person of 97% can measure a month after 3 needles to still maintain the 2nd year to exterior antibody; fall the 3rd year in; of this one level 74% the left and right sides, antibody drop is spent also drop. Whether to need again vaccination, advocate after if want to determining,the drop of antibody of second liver surface is spent, when does the decision make second liver vaccine again. Antibody drop spends second liver surface to be less than or be equal to 10 international unit / milliliter person, should be inside half an year vaccinal. Antibody drop is spent be more than 10 international unit / milliliter can be inside 6 years multiple cropping. The most scholar of our country suggests immune hind is strengthened 1 times inside 3 years had better. 6, can be second liver vaccine used at the same time with other vaccine? Second liver vaccine can be mixed vaccine drifting a head, BCG vaccine, white second head is vaccine of grey matter of 100 broken, spinal cord, vaccinal at the same time vaccinal, vaccinal program undertakes according to the order that plans immune place requirement. But second liver vaccine had better not be used at the same time with measles vaccine. 7, how does the person that contact second liver virus accidentally make second liver vaccine? (1) is right not vaccinal the too vaccinal person that contact, inject first globulin of second liver immunity (the) inside 24 hours, next vaccinal second liver is vaccinal (1 week of) after hitting globulin of second liver immunity. (If 2) is contacted person vaccinal already too vaccinal, but without whole journey immunity, program of immunization of second liver vaccine should be pressed to fill after globulin of immunity of inject second liver on whole journey immunity. (3) have an inoculation is too vaccinal, already produced the contact person of antibody of second liver surface, answer to be decided according to its antibody level. If level of antibody of second liver surface is adequate but need not handle; level to should strengthen 1 needle of inject not quite vaccinal; if the first time immunity should inject as early as possible without respondent globulin of second liver immunity and second liver vaccine each 1 needle. 8, can be vaccine of vaccinal second liver infected on other contagion? Vaccinal hepatitis vaccine won't cause other hepatitis to happen, also won't be infected to go up other disease. Second liver vaccine has strict quality level in producing a course, AIDS virus includes in making multitask foreword can kill blood among them inside cause of disease is microbial, passing clinical observation is on the safe side. Those who be worth to put forward is, if use rejected product is degenerative and inject damaged, vaccinal, or injection process does not ask to operate by asepsis, common injector or pinhead, can acquire hepatitis or other infection. Still having one part person is recessive so the person that infect, virus assumes low-level duplicate position, "Two half-and-half " the examination is regular, need arises virus with check of law of ribonucleic acid hyperplasia (HBVDNA electropositive) , this kind of person won't have exterior antibody to form after inject is vaccinal. 9, if be in outlying area, is the general that cannot still accomplish second liver vaccine planted how to do? Should be opposite at least the easy feeling crowd that is in quicksand of height of second liver virus below undertakes have an inoculation of second liver vaccine: Whole new life the staff member of child; dangerous occupational with nursery school (dialytic room, blood station, nursery governess waits contagion, department of stomatology, blood a moment) virus of liver of second of; of the person that the patient; before the military; organ of new enrollment of; of the person that; uses haemal product transplants needs to use immune depressor for a long time. 10, is second liver patient had necessary is the liver that make second vaccinal? The person that second liver vaccine is carried to virus of second liver patient and second liver does not have precautionary effect, no matter make vaccine of liver of how many second, won't produce corresponding protection antibody -- antibody of surface of second liver virus, just waste vaccine and funds just. Right as a result of the person that contract second liver virus before and obtain effective protection antibody already naturally now (second liver " 2 half-and-half " examination surface antibody shows electropositive) , do not have more necessary again vaccination, nevertheless hind of have an inoculation also won't produce undesirable deputy reaction, level of antibody of surface of its second liver may somewhat heighten. If be patient of acute second liver, via be cured completely after active cure and recovering, virus of examination second liver " 2 half-and-half " exterior antigen already shade turns, remain core antibody to be masculine gender only, and the antibody of surface of second liver virus of protection from beginning to end cannot oneself arise, below this kind of circumstance, can inject second liver is vaccinal, make exterior antibody generation, make second liver is gotten no longer after oneself. (the exercitation edits: Plum apricot)
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