How does poison of second liver disease-resistant accomplish science to use drug?

How does the second liver patient of cirrhosis of amalgamative and inchoate liver undertake inchoate liver cirrhosis is to although appeared,point to liver fighting virus to treat 　 ill rational change, but hepatic function still is in acting countervail period (class of liver function Child-PughA) . Right now, the patient can have longitudinal lack of power, anorexia or abdominal distension symptom, its transaminase also can have unusual change, but the patient still breaks acting countervail to behave without apparent liver function. In addition, patient of inchoate liver cirrhosis still can have portal vein high pressure to ask for, if lienal function hyperfunction is reached,spend the varicosity end esophagus stomach gently, but the varicosity end its esophagus stomach won't develop to bleed for burst, the patient also won't appear the complication such as ascites and disease of liver sex brain. Although the patient attributes level of inchoate liver cirrhosis right now, but if the second liver virus inside its body is duplicate,index shows masculine gender (the direct element that this often is illness accentuation) , need to undertake disease-resistant poison is treated so, the second liver of cirrhosis of amalgamative and inchoate liver " big 3 this world " patient, its undertake those who refuse virus treatment point to ask for virus of the liver that it is second to DNA is more than or be equal to milliliter of 105 copies ／ . And the second liver of cirrhosis of amalgamative and inchoate liver " small 3 this world " patient, its undertake those who refuse virus treatment point to ask for virus of the liver that it is second to DNA is more than or be equal to milliliter of 104 copies ／ . The cause that these two kinds of patients treat all is the happening that defers liver function to miss acting countervail and liver cancer, the medicaments that can choose and its usage are as follows: 1. Rummy husband decides: Patient but every time profess to convinced this medicine 100 milligram, daily take. This medicine needs to be used for a long time, meantime patient cannot do sth without authorization stops drug. If the result of this cure is favorable, the patient can be obtained continuously respondent. 2. Ester of A Defu Wei: Patient but every time profess to convinced this medicine 10 milligram, daily take. When the second liver patient of cirrhosis of amalgamative and inchoate liver is undertaking disease-resistant poison is treated but first selection this medicine, also can treat unsuccessful hind to choose this drug surely in use rummy husband, and need to be taken for a long time. 3. Favour for Ka Wei: Patient but every time profess to convinced this medicine 0. 5 milligram, daily take. Same, when the second liver patient of cirrhosis of amalgamative and inchoate liver is undertaking disease-resistant poison is treated OK also first selection this medicine, still can decide the reelection after cure fails to use this drug in use rummy husband, and need to be taken for a long time. 4. Interferon: Because use this medicine to be able to make patient occurrence liver function breaks the complication such as acting countervail, accordingly, if the second liver patient of cirrhosis of amalgamative and inchoate liver must use this drug, answer as a child dosage begins, next according to oneself be able to bear or endure suffer a circumstance to increase dosage gradually. How does the second liver patient of terminal liver cirrhosis in incorporating undertake disease-resistant poison is treated terminal liver is sclerotic in 　 , the countervail missing generation that says on medicine namely period liver is sclerotic (class of liver function Child-PughB, C) . Patient of cirrhosis of this kind of liver often produces the serious complication such as disease of brain of sex of haemorrhage of burst of the varicosity end esophagus stomach, liver, ascites, and still can apparent liver function breaks acting countervail performance, if serum albumin is less than 35 grams,／ rises, bilirubin is more than 35 small rub Er ／ rises, the activity of the zymogen of elevatory, cruor that transaminase has different rate is spent (PTA) be less than 60 ％ . Although incorporate in the second liver patient of terminal liver cirrhosis is undertaking cure is not fighting virus right now is good opportunity, but if its are hepatic inflammation is apparent, and transaminase and bilirubin are remarkable and elevatory, can try to undertake disease-resistant poison is treated. Patient of cirrhosis of this kind of liver undertakes fighting virus remedial point to ask for DNA of virus of the liver that it is second to show masculine gender and liver function is unusual. The cause that its treat is to pass those who restrain the virus inside body is duplicate will improve liver function, be deferred thereby or prevent operation of the transplanting that do liver. What need points out is, the second liver patient of terminal liver cirrhosis in incorporating undertakes cure can delay the progress of the disease only fighting virus, unalterable its can develop finally for eventually the ending of evening liver cirrhosis. Because interferon can bring about liver exhaustion, so this medicine does not suit this kind of patient to use. Duplicate to the virus inside body active break acting countervail with what have inflammation activity patient of period liver cirrhosis, below the circumstance that in its know the inside story agrees with, can use rummy husband to have treatment surely, in order to improve its liver function, but cannot stop drug at will. Once the virus inside system of this kind of patient produces mutation, should add in time with other already approved those who use, the nucleotide that can defy virus mutates (acerbity) analogue, if ester of A Defu Wei or favour replace Ka Wei. (responsibility edits: King sea E)