Affect 4 factors that second liver cures

　 of misgivings of 1 comfortable be recruited no matter interferon or rummy husband are decided, have strict comfortable be recruited, the person of virus of liver of second of not all infection can apply. The comfortable be recruited with these two kinds of collective medicine is patient of chronic second liver, transaminase rises the 2 ～ that are as high as normal value upper limit 10 times, hepatic inflammation response is apparent person. At this moment the patient is in " immunity is cleared period " , namely the immune function inside body is started, initiate to second liver virus encircle and suppress and cleared, right now applied disease-resistant bane aids a helping hand, the effect is distinct. In " immunity is able to bear or endure suffer period " , transaminase normal or a few is worth normally more than, hepatic inflammation light or without, for example the person that second liver virus is carried, function of the immunity inside body is right second liver virus " pay no attention " , using any disease-resistant poison at this moment also is futile, to this, the effect that husband of interferon, rummy decides is very finite. If choice of comfortable be recruited is accurate, curative effect can rise apparently, the choice is undeserved, excessive " interference " , excessive fights poison, not only cannot get satisfactory curative effect, return the remedial hope that meets contusion patient, or antagonism virus cure generates resentment, make " disease-resistant poison is invalid theory " , patient of influence second liver uses drug normally. Medicaments of virus of the 2 liver that fight second has limitation 　 chronic second liver is not use interferon or rummy husband to decide with respect to everything is just fine, not be to use medical hind to be able to recover certainly more. Actually, medicine of virus of the liver that fight second has its limitation, the primitive pattern plate with duplicate to second liver virus bane of current and all disease-resistant (CccDNA) is invalid, once stop drug, second liver virus continues very quickly to duplicate for pattern plate with CccDNA, the result is many virus of liver of new student second rampant rise, cause liver disease to have a relapse. Medical home people point out, if insist to use drug for a long time, of the virus inside body of utmost ground suppress duplicate, participate in plus the immune function of oneself, just can keep clear of virus finally, the patient just recovers likely. Another limitation of medicine of virus of the liver that fight second is opposite for the patient its " respondent rate " not be 100 ％ (respondent the HBeAg after showing the patient uses drug turns shade, fight - HBe turns in relief, HB-VDNA turns shade, transaminase is normal) , interferon treats chronic second liver " respondent rate " control in 40 ％ , and long-dated and respondent rate is controlled for 30 ％ only. When rummy husband treats chronic second liver surely, use drug 1 year, HBeAg turns shade rate is less than 20 ％ , happen fight - HBe turns in relief person only 15 ％ left and right sides, although HBVDNA turns,shade rate is as high as 96 ％ ～ 100 ％ , but HBeAg does not turn shade or fight - HBe does not turn in relief, have a relapse easily. Accordingly, we should see the validity of disease-resistant bane already, also want to know its limitation, know these medicaments correctly, cannot because of its " limitation " and those who abandon need not, also cannot because of its " effective " and blind and hopeful. The poisonous side-effect of 3 medicaments 　 　 " it is medicine 3 minutes poison " , medicine of virus of the liver that fight second is poisonous also side-effect, this often because of the person different. Applied interferon is divided can cause flu appearance disease group besides, still can cause leucocyte, plaque to decrease, also have trichomadesis, depressed wait for circumstance happening, because poisonous side-effect makes,treat suffer a setback sometimes. Rummy husband can cause reaction of gastric bowel path sometimes surely. These can make patient immunity ability drops, cause remedial failure. Liver of chronic second of 　 of mutation of virus of 4 second liver is a complex and changeful disease, in disease-resistant bane content action falls and pressure of human body immunity falls, virus often produces mutation, this can cause remedial failure. Remedial process patient's condition of medium, patient often also fluctuates, appear repeatedly, this does not ascribe to certainly the application of disease-resistant bane content. Additional, the immune function of patient of chronic second liver is maladjusted, can happen in cure " mixture infection " , be like liver of third of second liver ＋ , fourth liver of second liver ＋ , liver of armour of second liver ＋ , or second liver is amalgamative fatty liver, sometimes because abuse drug, drink etc, make an illness complex, cure is more difficult, this is not the fault of disease-resistant bane. Analyse and find measure of unsuccessful reason reassume, still can obtain curative effect. In using process of drug of virus of the liver that fight second, want meticulous observation, analyse with all possible means, medicine of virus of the liver that fight second is not " all-purpose spirit medicine " , if other remedy fights liver fiber to change, adjust of immune function respect auxiliary using drug also is very necessary. Remedial second liver fails, cannot fight virus medicaments in the negative, everybody also cannot make excessive demands disease-resistant bane. Second liver is therapeutic develop up to now, the greatest progress is establish the comprehensive treatment strategy that disease-resistant poison gives priority to, if do not go fighting virus, be about the road back to one's former position, patient of liver of 1 billion second not know what to do. Of course, to the inadequacy of disease-resistant bane, the scientist is aware of already, studying deep now and develop more effective disease-resistant bane, ought to say foreground is hopeful. (responsibility edits: King sea E)