Saturday, 17 February 2007
It is difficult that liver of second liver third mixes infection make do
The cure of chronic second liver still is at present " long-standing " , and the mixture infection of chronic second liver and third liver is more difficult medium difficult. Alleged mixture infection shows a patient affected second liver virus to contract third liver virus again already namely. Investigation is informed, mixture infection of liver of second, third is occupied about in chronic second liver 10% , chronic second liver shows a patient about 30 million, so the whole nation has 3 million person about is mixture infection of liver of second, third. Though α interferon is right,second liver virus and third liver virus have the remedy of effect at the same time, but the curative effect in applying actually very not ideal. According to research, OK between virus of liver of the second inside human body and third liver virus interaction, affect the curative effect of α interferon thereby. Somebody observes discovery, after liver of second, third mixes infection to use interferon, its curative effect is apparent under respective onefold infection. After patient inject recombines α interferon, investigator discovery, third liver virus is kept clear of, and second liver virus is activationed however. Also somebody discovers, shade of nucleic acid of virus of liver of the second after applying α interferon turns, but appeared subsequently nucleic acid of third liver virus, and appeared apparent symptom and even happen icteric, patient patient's condition accentuated. So, concerned expert does not advocate the interferon that use α treats liver of second, third to mix infection more. Current, treat chronic second liver, experts recommend use rummy husband to decide, it is analogue of a kind of nucleotide, have apparent inhibition to nucleic acid of second liver virus, somebody to enhance curative effect, adopt rummy husband to combine α interferon to treat chronic second liver surely. Say normally, these two kinds of medicine are right the action of second liver virus the point is different, associated application should have synergism, but the fact is not such, both couplet uses the curative effect that treats second liver surely with rummy husband with sheet and nonsignificant difference. Nevertheless, we discover in clinical practice, the curative effect that rummy husband combines α interferon to treat liver of second, third to mix infection surely is better. If have the transaminase of one patient all the year round abnormal, in the begining we do not know this is mixture infection of liver of a second, third, virus index checks to just be informed this one circumstance in be being treated. After we are decided in husband of associated application rummy and α interferon treats 3 months, the effect is very ideal, patient transaminase is normal, the symptom disappears, and nucleic acid of second liver virus also turns for negative. At this moment we increase α interferon dosage to come 5 million unit / second, nucleic acid of virus of result third liver also shade turned. 3 when treat subsequently mix infection patient, achieve " completely respondent " . We are suppositional, the likelihood is rummy husband is decided puissant restrain nucleic acid of second liver virus, and interferon of large dose α basically is to restrain nucleic acid of third liver virus, two kinds of medicaments are inside human body " each doing his own job " , won't arise " activation " action. (the exercitation edits: Plum apricot)
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