Tuesday, 20 February 2007
Second liver needs Shen Zhi with medicine jointly again careful
Virus of the liver that fight second (the associated application of HBV) medicaments is in clinical more general, but, our country announced 2005 " guideline of prevention and cure of chronic hepatitis B " the associated application that did not recommend disease-resistant bane content. American liver is ill 2007 of association " chronic hepatitis B is clinical carry out a guideline " the delibrate material that with the United States concerned expert of national and wholesome academy publishs, also do not maintain associated application. Two kinds of nucleotide kind medicaments couplet is used and use unlike sheet among them a kind more effective. Sheet decides group and rummy husband to combine constituent of ester of A Defu Wei not to treat patient of chronic second liver surely with rummy husband, when going to the 52nd week, the fall of HBVDNA and HBeAg turn shade rate, two groups do not have distinction. But transaminase (of ALT) answer constant rate appears however change, sheet decides group answer to often be led with rummy husband for 70% , associated application form has 48% only. Accordingly, nucleotide kind fight the couplet between HBV medicaments to use should not advocate. Nucleotide kind with interferon kind the associated application that refuses HBV medicaments, also be not advocated. In the research of a multinational efforts, patient of liver of chronic to 226 second has treatment, the HBeAg/ that common interferon combines rummy husband to decide remedial form is fought - HBe changeover rate is 36% , sheet decides the changeover of the group to lead with rummy husband for 22% , sheet uses common interferon group for 19% , the surface looks have certain difference, but in follow for a long time there is apparent difference however in visitting. Because this experts think, associated application both won't heighten curative effect. Fight HBV medicaments couplet to remain to prove with Chinese herbal medicine. Of our country " guideline of prevention and cure of chronic hepatitis B " in point out clearly: "Chinese traditional medicine of doctor of traditional Chinese medicine treats chronic second liver to be in our country application is wide, but most medicaments lack contrasts strictly randomly research, its fight virus curative effect to still need farther test and verify. " this is an objective assessment. Add blindly using Chinese herbal medicine is the economic burden that can increase a patient, 2 it is to may cause loss of medicaments sex liver. Associated application fights HBV medicaments to be in the likelihood will be direction henceforth, as fighting AIDS poisonous " cocktail therapeutics " same, but return at present very immature, lack is approbated extensively " associated plan " . The expert thinks, circumstance of the following minority also can use disease-resistant bane thing jointly. Be able to bear or endure surely to rummy husband when medicine, can apply ester of A Defu Wei and rummy husband to continue to treat surely jointly. To Adefuwei ester is able to bear or endure when medicine, can apply rummy jointly the husband is decided and ester of A Defu Wei continues to treat. Break cirrhosis of liver of acting countervail sex to second liver, also can apply rummy husband to get blessing Wei ester to have treatment with A surely jointly. To the jackknife infection of virus of second liver, third liver, if two kinds of virus are duplicate active, nucleotide of combination of usable interferon length effect kind medication. (the exercitation edits: Plum apricot)
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