How does chronic second liver choose disease-resistant poison?

When partial medicines and chemical reagents produces manufacturer to publicize its product on the media such as broadcast, TV, newspaper, also do his utmost after its medicines and chemical reagents uses advocate, can make patient serum HBsAg, HBeAg and HBV-DNA shade turn, make second liver is obtained effect a radical cure. Everybody is in the cause that treats second liver certainly " second liver turns shade " above, effect a radical cure with expecting to obtain, this is an error actually. Can be chronic hepatitis B effected a radical cure? To adult acute hepatitis B, great majority patient is OK self-healing (it is good to spend period of time like the cold) , final symptom disappears, liver function returns to normal, serum HBsAg disappears, serum HBsAb positive indicates second liver virus is kept clear of, this part person can say to obtain effect a radical cure. However at present socially patient of liver of great majority second is chronic second liver, cure for a long time hard. Actually chronic hepatitis B still is a kind of disease that cannot cure up to now, no matter be home or abroad, no matter be Chinese traditional medicine or Western medicine, still can make chronic hepatitis B complete without a kind of medicines and chemical reagents heal. HBV-DNA is virus of reflective second liver is duplicate " golden index " , and the ration that had better undertake HBV-DNA detects, conduce to the choice that treats plan and the judgement that combat virus curative effect. But shade of HBeAg, HBV-DNA turns to meant airframe to already kept clear of anything but virus, although blood is medium nonexistent virus, second liver virus still but inside the liver cell of consist in patient. Already approved the disease-resistant poison that appear on the market to treat medicaments to still cannot make major patient achieves HBsAg to keep clear of at present, because this fights virus at present,remedial terminus is ALT (amino move of third ammonia acid is enzymatic) return to normal, HBV-DNA shade turns and HBeAg serum is changed. Emphasize making with all sorts of medicaments blindly second liver virus each index shade turns, with period cure thoroughly, it is impossible. And because use medicine to be able to accentuate instead in great quantities hepatic burden, the liver of sex of hepatic occurrence medicaments that brings about a patient is damaged. How to choose disease-resistant bane content? Have the medicaments can be counted on one's fingers of better disease-resistant poisonous curative effect truly at present. The medicaments of the virus of the liver that fight second with accepted bound of current international medicine has analogue of α interferon, nucleotide. α interferon basically is aimed at serum HBeAg positive / electronegative but HBV-DNA positive, ALT is elevatory and normal the patient of chronic second liver that is worth 2 times above. The curative effect of common interferon is 20%30% about, already was in at present clinical on the lasting effect interferon that approval uses (PEG-IFNa-2a) curative effect is 30%45% about. Representative medicaments has nucleotide analogue rummy husband is decided, Adefuwei, favour replaces Ka Wei, and replace in what Chinese approval appears on the market recently need the husband is decided, getting used to card is serum ALT electropositive patient of elevatory, HBV-DNA, no matter its HBeAg is,masculine gender or negative all can be used. Nucleotide analogue but rapid and effective reduce serum HBV-DNA level, take convenient, security is good. But stop medical hind easy recrudesce, long-term application can bring about virus happening to mutate and appear be able to bear or endure medical phenomenon. As the development of science and technology, the knowledge that we send ill mechanism to chronic second liver is ceaseless and thorough, believe to be in before long we can conquer thoroughly certainly in the future chronic second liver. Final summary is the following: 1. Second liver still cannot be cured thoroughly at present; 2. Disease-resistant poison cure must master strictly get used to card; 3. Cure should be in next professional doctor is directive undertaking, do not certain advertisement publicizes believe what one hears, use drug blindly. (responsibility edits: King sea E)