Sunday, 18 February 2007
Disease-resistant is poisonous: Concept + medicaments + foreground
Liver virus (HBV) infection is a kind global the contagion that distributing. There are 1.2 ~ in China virus of liver of second of infection of 130 million person, among them patient of chronic hepatitis B (CHB) is 3000 ~ about 35 million person, there are 10% ~ among this 40% can develop the cirrhosis that it is liver, 1% ~ 5% can evolve for cancer of the liver. Die every year at dependency liver disease (include cancer of the liver) 800 thousand person of about 50 ~ . If second liver virus is passed perpendicular infect or affect in infantile period, 90% above can become the person that chronic HBsAg is carried, serious effect issues the health of generation, the harm is great. Poison of second liver disease-resistant " solve piece " the person that Nbsp; is affected to second liver virus, with what we fight virus after all? Concept is opposite at present the cure of patient of chronic hepatitis B, it is to use disease-resistant poison, immunity adjustment, improvement liver function is changed with the fiber that fight liver wait for comprehensive treatment, but among them key is disease-resistant poison to treat. Because disease-resistant poison treats the duplicate; that can restrain virus not only,this is and can improve liver function and hepatic inflammation, necrotic the life quality that changes pathological changes; to still can improve a patient with fiber and reduce its infectivity, make virus finally cleared, stop the happening of pathological changes, development, make ill caustic rehabilitate, block breaks development to be exhaustion of liver cirrhosis, liver function and liver cancer. This is the new concept that virus of liver of current antagonism second treats. After-thought before, we are treating the error that exists in second liver virus, scotoma, true still many. It is not to pay attention to cure of virus of the liver that fight second above all, think by accident transaminase (ALT) is the index with infectious clew unusually, think transaminase is taller, infectivity is stronger. Regretful is, this plants hold of wrong viewpoint, now still there are plenty of such people. They take seriously only fall transaminase, take no account of disease-resistant poison to treat; to fight virus to treat an opportunity to go up in the choice, always adopt measure to fall transaminase to first normal, or while disease-resistant poison is treated, add and so on of double ester of the benzene that use couplet to fall by force enzymatic medicaments. This makes a lot of patients missed best remedial opportunity. On the choice of medicaments of virus of the liver that fight second and method, some doctors or patient, do not wish to accept the α of medicine of disease-resistant poisonous first selection with accepted international - interferon, second choose analogue of medical new nucleotide, and ground of year in year out accepts Chinese traditional medicine to fight virus to treat, or want to be planted with some only medicaments, the problem is solved inside short time, the result can be only end in order to fail. Create economically waste to the patient not only so, still make they are on spirit incur very blooper, of sad disappointment, some still reachs " second liver did not rule by law " conclusion, with paralytic oneself. Medicaments is in of scientific and swift and violent development today, on cure of virus of the liver that fight second, already achieved a lot of new progress. Main lock decides present remedial method the following 3 kinds: (1) uses α - interferon and nucleotide are similar disease-resistant bane content, if rummy husband is decided, Adefuwei, Endekawei, undertake virus treats; fighting second liver (2) is like thymus element α with cellular factor 1, Bai Jiesu 12, γ - interferon, undertake immune adjustment treats; is not particularity (3) is used fight HBV to treat sexual vaccine, undertake particularity immunity is treated. Particularity immunity therapeutics is right second liver virus, it is a kind of brand-new therapeutics really, the immunity that its characteristic is the person that it can break virus of chronic second liver to affect is able to bear or endure suffer, fall in the case with cereal third not high transaminase that is to say, yi Ke accepts this kind of treatment. Be in our country, particularity immunity therapeutics is to won approval of national Ministry of Public Health in September 1998, by association of technology of Chinese medicine biology group of clinical research efforts, the organization uses gene to recombine antigen of second liver surface about the unit (the remedial sex that HBsAg) makes is vaccinal. Observe the person that treat virus of chronic second liver to carry early or late 370, the result makes HBsAg, HBeAg and HBV DNA shade turn rate achieve respectively 14.7% , 30.0% with 37.3% , curative effect is better, contrast with the corresponding period group of photograph comparing, difference is notable. This kind of method is very safe still, did not produce your patient to cannot be able to bear or endure up to now the deputy response that get, deserve further research, current, the total cause that fighting hepatitis B cure to can be achieved and hard. On the ill meeting of liver of the 39th Europe that foreground held in April 2004, have expert story: Sheet uses Adefuwei, can make partial patient HBsAg, HBV DNA turns shade, ALT returns to normal. In changing thing treatment to pass Cheng with ester of A Defu Wei, 90% above patient can maintain HBeAg serum changeover. Additional, get together second 2 alcoholize interferon α - 2a(sends Luo Xin) sheet is used, also can produce more respondent than rummy husband lasts high surely rate. The author combines thymus peptide with this medicine - α 1(base peaceful) liver of remedial slow second 6, among them already a HBsAg turns shade, additional a HBsAg also already by the strong positive before cure, to the weak positive when treating 5 months. Preliminary look already showed better symptom. If can cooperate aforementioned again distinctive cure sex is vaccinal, its curative effect will better. It is reported, at present our country is clutching the DNA vaccine of development, tree dash forward the remedial sex such as vaccine is vaccinal, foreground is valued. So, although prospect is difficult not little, but second liver patient is not this disappointment however, because science and technology always is advancing, calm meeting will excel now tomorrow. Recommend; Poison of disease-resistant of liver of 10 things second uses poison of second liver disease-resistant medical total strategy (the exercitation edits: Plum apricot)
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