Saturday, 10 February 2007
Shallow talk about gestation disease-resistant poison to treat
"Drop drop " sound hints I am new get a short message, open look, a Juan sends me, writing above " thank a doctor, I had, but I am taking rummy husband to decide, how to do? " the patient that A Juan is me, the woman with this young and beautiful, amiable disposition has the superior domestic environment, husband that is very fond of her and a good cause, if not was to get chronic hepatitis B, you can feel God is honest too deep love she. A year half before, a Juan's hepatitis breaks out, come check when go to a doctor here: Big 3 this world, HBV DNA107, ALT180ULN, ask for those who get her to agree at that time, I give her prescription the rummy husband of virus of the liver that fight second is decided, period of treatment is provisional be in two years, during this, requirement she every 3 months will be checked. A Juan's treatment is very successful, taking the first month of medicine, HBV DNA and ALT had turned for negative, the HBeAg of the 9th month that treating also turns for negative, I encourage her to continue to take drug, wait for HBeAb to turn to begin to consider to stop drug for the ability after masculine gender. Current treatment is showing effect partly, who knows to be on this vital link, she was pregnant unluckily, is now to stop medicine to still continue to use drug? Should stop gravid? This can be a difficult problem really! Data shows: The person that our country has second Gan disease to affect more than 100000000 people, the second liver patient with the person that this includes various second liver virus to carry and illness differ weight, among them great majority (60%- - 80%) originates the perpendicular transmission of familial sex, namely so called Mu Ying is perpendicular transmission and father baby are perpendicular transmission. How does the person that does the detail enter Gt;gt; second liver give birth to healthy darling? In my old practise medicine career, how does the woman of Yo age treat chronic hepatitis B, it is a very thorny difficult problem. The cure of this one phase has two objectives: Itself of Yo age woman hopes second liver can receive effective treatment, the Mu Ying that; bears to hope to reduce hepatitis at the same time as early as possible after waiting for a disease to stabilize travels. The Mu Ying that how reduces hepatitis effectively travels, with respect to current medical technology, this is solved not hard. Research makes clear, the odds that the infection inside palace appears during patient of chronic second liver is pregnant is very low (make an appointment with 5%) , accordingly, hepatitis is inactive during patient of chronic second liver should is pregnant only, whole period of treatment requires treatment scarcely, should use dig abdomen to produce when childbirth only shorten produce Cheng, reduce the chance that blood of Mu Ying happening exchanges, give a new life inside 12 hours at the same time globulin of immunity of vaccinal second liver (dosage Gt;100IU) and use 0, 1, 6 plan (namely new student those who be born that day, the 6th the first month, month) vaccinal second liver is vaccinal, but effective block breaks Mu Ying to travel, businesslike amount to 90% above. Rummy husband is decided, was used at treating chronic second liver by FDA and approval of our country SFDA 1998. Because its combat virus curative effect exact, security good, profess to convinced the element such as convenient, economy is used extensively. But the second liver patient that has partial Yo age, appear during use rummy husband is treated surely gravid, how should choose? One part expert suggests to stop drug. Because lack rummy husband to decide the detailed data that studies to pregnant woman and fetal security at present, and gravid it is a very complex physiology process, the factor of body state of parents, genetic material, environment is possible during this the decision is fetal healthy, in this complex element plus the medicaments that taking, influencing factor is too much. Possible reason lays healthy person unidentifiedly patient of liver of second of defective child; is gravid during taking drug bear, if yield defective child, it is after all still mix related to the medicaments that taking other factor is relevant, very it's hard to say is clear. But after stopping drug, whether can the hepatitis of pregnant woman have a relapse? Pregnant woman whether overshoot in safety endless gestation? The risk during this is very big also. Also one part expert thinks, in the course that second liver patient is taking rummy husband to decide gravid bear, the risk is not quite big also. Because rummy husband decides 150mg to also be used at the cure of AIDS, at present the AIDS of the United States and China recommends rummy husband to be used at block to break Mu Ying to travel surely in guideline of prevention and cure, did not see right fetal influential report. Be in our country, zhejiang medical university is accessary 2002 in division and department of gynaecology and obstetrics ever observed jointly and reporting the process that the patient of chronic second liver that has 42 is accepting rummy husband to be treated surely, the contagion of the first hospital discovers early pregnant, via seeking advice, patient and family member selection are as follows: Exemple of;2 of induced abortion of a choice chooses to stop medical;1 exemple to break visit; to 38 choices continue gravid, hold to rummy husband to decide remedy at the same time. As a result these 38 patients produce mother baby complication without (abortion, slink, new student asphyxial, stillborn foetus and fetal deformation) , poisonous occurence rate of infantile in spite of illness is 0, along with visit a year, also did not discover infant development is unusual circumstance. Divide however besides medical viewpoint, still have even if consider the issue of interest and risk. If the patient is young, it is not difficult to become pregnant again, that undeserved adventure takes drug in gravid process, still suggest to insist to treat hepatitis to stabilize, after stopping drug, plan again gravid bear. If the patient limitation as a result of body condition, the odds that becomes pregnant again is very low, and birth desire very intense word, after signalling afore-mentioned medical point of views, final power to make decisions is handed in in patient and family member hand normally. Pregnant woman reads surely 3 measure block breaks baby of second liver mother to transmit vaccine of vaccinal second liver is liver of the most effective second of of the method that prevent disease disease-resistant poison also wants when pregnant woman comes on liver of second of most pregnant woman is do not need to stop gravid second liver pregnant woman is OK lactation, do not increase a baby to affect the dangerous sex of second liver virus. (the exercitation edits: Plum apricot)
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