Accidental medium inevitable - the discovery of HBV course

Professor Blumberg goes out in report middle finger, the discovery of HBV and the development with subsequently vaccinal HBV originate at first the basic research of concerned serum protein, and did not expect this one research and second liver domain to have so big dependency at that time in fact. Before Blumberg is taught, a lot of scientists try to discover the cause of disease that causes hepatitis microbial, but all do not have a result. Blumberg basically studies the heredity of serum antigen is much at that time the relation of easy sensibility of voice sex and disease. They use immunity to diffuse technology, the patient to ever accepting give aid and support for many times (like patient of hemophiliac, leukaemia) haemal sample undertakes study. He discovered 1963, the serum of a hemophiliac that lives in new York but with serum of an Australia native medium antigen produces reaction. Because this kind of antigen is of a discovery in preexistence Australia person, because this Blumberg weighs his,be Australian antigen. Blumberg undertook study to this in a lot of crowds again later, discover this kind of antigen is in Asia and African crowd positive rate is higher, and positive in Euramerican and healthy crowd rate is inferior, but positive in the Euramerican multitude that has liver ill feature rate is higher also. The Blumberg impact that still studied Australian antigen and leukaemia are asked for integratedly with Tang, rate of positive of antigen of the Australia in discovering Tang solicits a little patient integratedly is higher, and if antigen of Australia of little patient parents is electropositive, the little patient still can happen without icteric sex hepatitis. According to these clew, the hypothesis Australia antigen such as Blumberg and hepatitis are concerned, the research later confirmed Australian antigen is the one part of HBV really, namely HBsAg. Observe through the electron microscope later and infect an experiment to confirm, the virus that concerns with Australian antigen can cause hepatitis really. Will look from this, the whole discovery of HBV the process is not designed good beforehand, the result that discovers accidentally for many times however. Consider to discover later, the HBsAg in the person's serum exists at the same time with HBsAb rarely, and HBsAb is electropositive person have immune effect to HBV really. Blumberg and Professor Millman use specific technology to part HBsAg and virus, undertake HBsAg decreasing poison to destroy living, this is the vaccinal first course that make, of course, the second liver vaccine that uses extensively in vaccinate now is the antigen of second liver surface that uses gene to recombine a method to convey. Current, HBV already was become worldwide inside one of the commonnest infection causes, the number that dies every year because of HBV relevant disease makes an appointment with 60~100 10 thousand, although HBV influences ill dead rate (15%~25%) is affected under HIV (100%) , but number of the person that affect as a result of HBV is numerous, because of this death gross (5570~9280 10 thousand) the person that far outclass is affected at HIV to death (34 million) . Those who make a person glad is, as the promotion that have an inoculation of immunity of second liver vaccine plans, HBV affects occurence rate to already dropped significantly. China begins to execute have an inoculation of infantile HBV vaccinal immunity to plan from 1986 up to now, ever vaccinal second liver is vaccinal person the 16.3%(879/5397 exemple that rate of HBsAg serum positive already contrasted by the history) fall to 1.43%(transverse research) study) with 1.81%(alignment. The fall that positive of the HBsAg in vaccinal crowd leads also can be affected secondhand not vaccinal person with easy feeling crowd. Italian research makes clear, major member not the rate of positive of group HBsAg serum of vaccination also falls somewhat, hint the precautionary effect of vaccinal have an inoculation has enlarge effect. In addition, HBV vaccinal have an inoculation still can prevent the happening of liver cell cancer, the research of Chinese Taiwan, Korea and Canada all confirmed this. Blumberg teachs final appeal, the foundation is current circumstance, not only should continue to popularize have an inoculation of second liver vaccine, in order to prevent the happening of second liver, take the therapy of virus of effective the liver that fight second even, if we control HBV DNA standard can strongly, can reduce its infectivity, final second liver infects a number to will decrease further. Character of legend of 　 of school of careful of hospital of friendship of Beijing of manage of Hao Ran Zheng Professor Gu Jidong - long parted of nobel prize gainer arrives at liver of chronic second of Chinese Shanghai 　 once more after 30 years virus of liver of initiative Yu Yi, although it exists in nature already, but the mankind has 40 short years only however to its understanding. The mysterious veil that who opened second liver virus first on human history be? Although he is not clinical doctor, but the discovery of the milepost type that does not have him, clinical doctor diagnoses infection of second liver virus impossibly, the mankind prevents second liver and the happening that reduce second liver with respect to have no way. The clinical doctor that believes liver of second of every make a diagnosis and give treatment on the world can know " of vaccine of " of virus of liver of second of " of antigen of surface of " second liver, " and " second liver the principal port of 3 words, and these 3 speeches are as famous as the scientist's achievement is relevant. Also be in as a result of him the outstanding contribution of second liver domain, he was awarded highest special honour 1976 -- Nobel medicine and physiological award, he is Baruch S. Professor Blumberg. Professor Blumberg arrived at Shanghai again on Feburary 25, 2006, attend rich road to decide China to appear on the market meeting, make splendid report. Favour for Ka Wei (rich road is decided) China appears on the market can hold ceremoniously at was in Shanghai on Feburary 25, 2006. Expert of liver of second of more than 500 China attended this grand meeting, more than 60 media reporter attends rich road to appear on the market surely press conference, 15 abroad honored guests are attended, honored guest of 5 specially invite made wonderful learning report. More information is asked advertent " Chinese medicine forum signs up for " on March 16 18~19 edition " academic grand meeting, grand celebration -- rich road decides China to appear on the market meeting series reports 2 " . (the exercitation edits: Plum apricot)