The start inflection point that second liver treats is terminal

Patient of what kind of chronic second liver needs treatment? What kind of medicaments should initiative cure choose? When to need to adjust remedial plan? How to adjust remedial plan? When can you stop drug? What does the need after stopping drug notice? With " start " " inflection point " and " terminal " as the analogy, ill expert of our country liver put forward poison of disease-resistant of patient of chronic second liver to treat first " route chart " concept. When ministry of medicine of academician of Chinese Academy of Engineering, Beijing University teachs Zhuang Hui to accept a reporter to interview in Hainan last weekend, say, a lot of second liver patients defy virus treats the effect anticipate unscientific, lack the patience that insists to use drug again. Second liver is treated " route chart " , it is to expect to be in actually medicaments of liver of domestic and international second is clinical on experiment foundation, make doctors and patients bilateral can build jointly " complete course of diseases manages " consciousness, in order to achieve the goal that second liver treats -- utmost ground is restrained for a long time or eliminate second liver virus, relieve liver cell inflammation the necrotic fiber that reach liver is changed. Medicaments choosing satisfy the need holds to liver of second of 　 of enough period of treatment to treat " route chart " reiterate, should according to liver of our country second " guideline of prevention and cure " requirement, the different comfortable be recruited that masters patient of negative of antigen of E antigen positive, E strictly to undertake disease-resistant poison is treated, the choice controls virus power strong, serological changeover leads tall, security good, virus is able to bear or endure the disease-resistant bane content with medical low occurence rate, hold to enough period of treatment. "If use nucleotide (acerbity) analogue undertakes disease-resistant poison is treated, the patient should hold to 2-3 at least year or longer, and after amounting to mark, also need to go to a hospital following regularly visit monitor. " Zhuang Hui academician emphasizes saying. "Inflection point " make clear this to Hunan adjusts plan 　 in time " route chart " a bit of the most fetching attention, be treat about second liver " inflection point " where, namely whether does the individual strategy that poison of every patient disease-resistant treats need to be adjusted ceaselessly, and in when node, how to undertake adjustment? Director of liver ill center internal medicine of infection of southern hospital of committee member of vice director of institute of catch a disease of move of China cure society, Guangzhou and Professor Hou Jinlin is replaced with disease-resistant bane content it is surely than the husband exemple point out, take drug 24 weeks are important " inflection point " : If right now nucleic acid of DNA(of second liver virus) fall not to detect, or virus holds an amount under 300 units, the patient does not need a change to treat plan, can lengthen at the same time along with if right now second liver virus carries a quantity to fall,visit removed; 300-1000 between the unit, the patient needs to strengthen along with visit, should consider to if right now second liver virus holds an amount,adjust remedial program; when necessary still prep above 1000 units person, need to shorten along with visit interval, add at the same time with other disease-resistant bane content or flat change medicine. Clinical data confirms, the virus when poison of second liver disease-resistant treats 24 weeks is restrained " achievement " , with the patient the curative effect after 2 years is shown closely related. If use,replace the word that decides 24 weeks to obtain powerful effect to restrain virus than the husband, its do not detect after two years nucleic acid of DNA(of second liver virus) person occupy 82% , the patient of E antigen positive of 46% realizes serum changeover, and only a few patient can happen be able to bear or endure medical case. "Gold " take not easily strive for academician of Zhuang Hui of 　 of best curative effect, Hou Jinlin to teach further explanation to say, if can realize exterior antigen to change,second liver is treated is best result of course, this was equivalent to an athlete if realize the serological changeover of E antigen,winning gold; , was equivalent to if can restrain second liver virus to make,winning silver medal; the DNA(nucleic acid of second liver virus) turn shade, was equivalent to winning bronze medal. "Go after exterior antigen changeover to say to most patient blindly not actual, this seems to seldom count an athlete to be able to take gold only same. " experts hope patient of chronic second liver can is opposite treat a disease the anticipation that the target has a science, not credulous misdirect, do not quit, hold to correct disease-resistant poison to treat, achieve best curative effect in order to strive for. Recommend related: Second liver is discontinuous poison of disease-resistant of remedial to tolerate evil is to abet it, second liver treats " leading role " (the exercitation edits: Plum apricot)