How does second liver medicaments judge curative effect

The methodological 　 with judgement whether effective remedy a medicaments, need to pass clinical trial before clinical applying. Those who judge a kind of medicaments is effective deny, want to pass science, strict clinical medicaments test. The item below should notice in the experiment: Remedial case of illness besides it is patient of true chronic second liver certainly (HBsAg positive exceeds half an year) outside, the case of illness of observation must much, had better be in 30 above. Should have contrast group, contrast the circumstance of group patient, be like sexual distinction (the female's curative effect is better) , the age (the curative effect of the old person is poorer) , the discretion of transaminase (tall person curative effect is better) , is sclerotic (amalgamative liver is sclerotic person curative effect is poorer) , must as basic as remedial group same. The serum of around of treatment of two groups of patients is best microtherm is refrigerant save, after stopping treatment, use in a lab same approve reagent, by same laboratory assistant detects, such ability reduce the error lowermost limit likely. Want to the analysis of curative effect comprehensive, not only should analyse single index, if E antigen shade turns,shade of rate, HBV-DNA turns shade of antigen of rate, surface turns this world of antibody of rate, E turns rate, ALT answer often is led etc, and should be asked for to the patient's symptom, body and all sorts of detecting index undertakes integration analysis, if the change of E antigen must be mixed,the metabolic union of HBV-DNA rises the analysis. Of two groups of patients all sorts of detecting the result must have statistical analysis, whether to have difference in order to judge its truly, whether to have curative effect truly namely. Not only should see near future curative effect, see long-dated curative effect even. Want a few different medical establishment to prove its have certain curative effect. Anyhow, experimental design wants science rigorous, use parallel of random, double blind, much center, electropositive medicaments to contrast as far as possible law. (the exercitation edits: Plum apricot)