Vaccination is added for liver " insurance lock "

Chronic hepatitis B is a kind of common disease, frequently-occurring disease, vaccine of vaccinal second liver is the basiccest measure that prevents second liver. Current, our country production and use second liver vaccine basically are divided to recombine (yeasty) second liver vaccine and recombine (Chinese shrewmouse is ovarian cell, CHO) second liver is vaccinal. Clinical go up to be used more recombine (yeasty) second liver is vaccinal, normally use method is: Every time 5ug just was born at 0() , 1(1 month) , 6(6 month) each inject. Tall danger crowd but right amount increase dosage. Before adult vaccinate, should check liver function and other people of number of second liver virus above all (namely the second liver that common weighs two half-and-half) . If antibody of second liver surface is electropositive and drop spend the person that be more than 10mIU/ml to if two half-and-half check second liver to all show negative,do not need inject; , liver function is normal, can press afore-mentioned " 0, 1, 6 " means undertakes have an inoculation of second liver vaccine. Why cannot antibody produce after health reminds 　 have an inoculation? The have an inoculation of 90% above person can produce protection antibody, but still have 5% ～ the have an inoculation of 10% person the antibody drop that cannot produce antibody or produces spends a level low, short of protects action, its reason has 5 to plant roughly -- , 　 　 1, the ability of individual immunity reaction that accepts vaccinal protection is low, cannot produce protection antibody. This is concerned with a lot of elements, like the age lack of big, fat, smoking, excessive drinking, immunity, immunity is able to bear or endure to suffer or be put in certain and chronic illness to wait, still may concern with genetic element in addition. 2, the dosage of inject vaccine is insufficient, fail to produce protection antibody. 3, the infection inside infantile palace. Affect the mother of second liver virus, its new student grain of second liver virus already was contained in blood, inject vaccine does not have protective effect. 4, contracts virus is mutation virus (have two half-and-half reagent cannot fish) , perhaps suffer feral model virus (it is OK to have two half-and-halves reagent fish) the mixture infection with mutation virus. This kind of patient may appear in detect antigen of surface of second liver virus (HBsAg) negative result, but had contracted second liver virus actually, should check antigen of second liver E further (HBeAg) or HBV-DNA with diagnose. 5, immune function blemish or low person antibody of not easy generation. Be like the person that apply immune depressor, the person that the organ transplants, person that AIDS is affected, need to take immune depressor for a long time, liver of these crowd inject second are vaccinal, exterior antibody form has 17.6% only into respondent rate, to these people, vaccine of inject second liver needs to increase dosage. How doesn't antibody appear to do after have an inoculation? The friend that protection antibody did not produce after vaccinal second liver is vaccinal is OK so do -- , 　 uses acute method to detect afresh. Detect of the technology backward, detect the method is not acute bring about possibly protection antibody already produced inside body but detect do not come out, mistake does not succeed for vaccinal have an inoculation, if the acute method such as enzymatic couplet immunity or radiative immunity will detect afresh,can use at this moment. Increase dose of second liver vaccine. If use,detect advancedly still did not discover antibody of surface of second liver virus arises after the technology, the dosage that can increase second liver vaccine (every time 10 μ G) , inject every months 1 times, inject in all Yi Ke of 3-4 second; uses other remedy to assist a method, if can improving the condition of immune force,fall (wait for immune adjustment medicaments like inject thymus peptide) vaccinal second liver is vaccinal. Certain the person that already contracted second liver virus, antigen of surface of virus of its second liver (the quantity of HBsAg) is very few, detect with what have the method is checked do not come out; or second liver virus has produced mutation, do not produce reaction with common reagent. Can detect below this kind of circumstance HBV-DNA, also can detect content of comprehensive mark of second liver virus, wait like HbeAg, HbeAb, HBcAg, if be masculine gender, explain infection passes second liver virus. Director Chen emphasizes, liver having second is familial history or the person that often contacts with second liver patient, should the vaccinal effect of vaccine of liver of special attention second. Have the children with the parental strange place of second liver, must inject in time after be born second liver is vaccinal, check vaccinal effect. What should vaccinal second notice after is liver vaccinal? Because liver of vaccinal already second is vaccinal,cannot treat sth lightly to hepatitis. Director Chen emphasizes, the HBsAb drop of the generation after inject is vaccinal spends the person in 10mIU/ml above, ability has significant precautionary effect. The antibody that produces after inject second liver is vaccinal can prevent infection of second liver virus only, the virus sex hepatitis such as liver of armour, third, fourth to such as, the fifth of the ten Heavenly Stem did not prevent action. In the meantime, whole journey have an inoculation is not after second liver is vaccinal can prevent HBV completely to affect, still should notice to avoid the fecal, blood with second liver patient and secretion contact in the life. When the person that carry with virus is contacted, also should notice to use fair chopsticks, cent to feed wait for a problem. The protection antibody of the generation after inject is vaccinal also is not permanent, answer to strengthen inject again below doctor guidance. Every have an inoculation person level of the antibody after liver is vaccinal has vaccinal second tall low, duration has long have short, the opportunity that contacts second liver patient has many little, the dangerous sex that contracts second liver virus is different also, accordingly, how long of second liver vaccine needs to strengthen have an inoculation to answer because of the person different. Should time after vaccinal second liver is vaccinal detect fight HBs to drip degree, if drip,spend be less than 10mIU/ml or show negative to should take corresponding step, notice individual sanitation defends at the same time, lest affect HBV. At present much to children view is in 3 ～ strengthen have an inoculation after 5 years. Whether does the adult need again vaccination, should determining the decision after the drop of antibody of second liver surface is spent, when be like HbsAb negative, should; of vaccine of liver of second of whole journey have an inoculation is like HBsAb drop to spend be less than 10mIU/ml to should strengthen have an inoculation, general inject 5 μ G can. (the exercitation edits: Plum apricot)