Of the liver that fight second " small Miao Miao "

Analytic personage thinks, from walk out of a lab to still compare distant 　 recently, medical board piece the prices that walked out of a your person to fix eyes upon, and those who have idea of vaccine of liver of remedial sex second appear on the market the company is after the dormancy that passes period of time, also appear " scenery " especially good. In the bookshops in succession conjecture whether project of test of second liver vaccine appears significant progress, more message personage calls Chongqing beer (the project studies vaccine of 600132) second liver 2 period undertake successful, anticipate the near future can have relevant verdict. So, does vaccine of liver of remedial sex second leave walk out of a lab to still have many after all far? Still be in 2 period 　 of clinical research 　 " at present project of second liver vaccine still is in mostly 2 period, how does the effect still need to await experimental conclusion. " Zou of negotiable securities of an ancient name for China is entered newly say. In speak of the near future concerning Chongqing beer 2 period when the rumor that clinical result is about to publish, zou Xin is entered express unlikely, because 2 period clinical need time one year at least, and near future stock rises cross be capital respect merely likely greatly to drive. According to the bulletin of ministry of science and technology, the double blind that volunteer of liver of 46 chronic second completed A form in June 2006 experiments, predict to will uncover blind this year in July. The personage inside course of study thinks, 2 period the crucial period that clinical research is research and development of vaccine of liver of Chongqing beer second, if this phase is clinical research is successful, if was not amounted to,vaccinal and follow-up research and development also will compare successful; accordingly expect the result, will must undertake correction to early days research and development, have clinical observation afresh. Biology of cause of disease of college of medicine of Beijing University foundation fastens professor Zhuang Hui to ever expressed, "Although II period is clinical test result is right, still have III period clinical trial, the most hopeful estimation also wants to wait on 5-10 year. " 　 it is reported, the remedial sex of celestial bodies of beautiful of Chongqing of Chongqing beer subsidiary synthesizes vaccine of peptide second liver, it is to use Professor Wu Yuzhang of the third Military Medical University to be based on second liver antigen to express technical course, study at announcing the Ⅱ that start is clinical in March 2006. Show level other to involve those who treat vaccine of sexual second liver to appear on the market the company still includes Yue to amount to investment (industry of drug of 600805) , Guangzhou (biology of 600332) , the Temple of Heaven (600161) . Among them, yue amounts to investment and Fudan University joint-stock establish Shanghai answer to dawn company of company of technology of Yue Dasheng content undertakes liver of second of Wen Yumei group treats sexual vaccine (second is overcome) project research, this are vaccinal 2 period clinical trial already was started inside countrywide limits in September 2005, according to ministry of national science and technology the bulletin October 2006, shanghai Fudan University has prepared to start III period clinical trial; and Guangzhou drug industry controls share company the DNA of liver of remedial sex second of Bai Di and development of hospital of Guangzhou air force is vaccinal, classics SFDA was approved a few days ago, enter clinical research, this is home approves the DNA vaccine that is used at human body to experiment first. Diverse line 　 is current, our country is treating vaccine of sexual second liver to study a project in what begin, the albumen that basically includes to present as leading role by academician of Wen Yumei of Fudan University of Professor Wu Yuzhang of the third Military Medical University, Shanghai (peptide kind) vaccinal, and the vaccine of DNA of liver of remedial sex second of hospital of Guangzhou air force. Both design train of thought is different, one is a kind of antigen - antibody is compound model vaccinal, the immunity that the purpose is activation human body is respondent, another is to use peptide of a kind of synthesis to will invade the second liver virus inside body " shoot dead on the spot " . In promoting Wang Bin of researcher of industry of medicine of job negotiable security to report in its, express, the second gram that answer dawn Yue amounts to and peptide of Chongqing beer synthesis are vaccinal, belong to a kind substantially, it is albumen (peptide kind) vaccinal, because of alleged peptide kind with protein it is comprise by amino acid, main distinction is former contained amino acerbity number is less just. DNA vaccine also calls nucleic acid vaccine, it is to use gene to recombine a technology to will code some is planted directly of antigen protein outside source gene (after DNA) and plasmid recombine, guide directly inside animal cell, the transcribe system that adopts host cell synthesizes antigen protein, revulsive host generation is respondent to the immunity of this antigen protein, in order to achieve precaution and the goal that treat a disease. According to Introduction Wang Bin, the DNA of Guangzhou drug industry is vaccinal, belong to nucleic acid vaccine. From theoretic say, albumen (or peptide kind) the ability of immunity of cell of vaccinal and revulsive airframe is weaker, and DNA vaccine because imitate the process of virus infection airframe, but immunity of cell of particularity of generation of effective and revulsive airframe. Theoretic, DNA vaccine uses the root of oneself immunity function of airframe more likely to wipe virus, curative effect is better. The alluring 　 of huge market occupies authoritative branch statistic, the medical treatment pay that our country is treating field of virus sex hepatitis every year comes 50 billion yuan in 30 billion yuan between. Current, the person that our country has hepatitis B virus to carry is close 130 million person, patient showing disease exceeds 30 million person, still 100 million above fights yuan of positive without semiotic HbsAg(surface) the person that carry, second liver incidence of a disease is maintaining the momentum that resides Gao Hezeng to grow, only the patient of 19% is accepting the remedial method that gives priority to with fighting virus to treat, be as high as what the patient of 73% uses is to protect liver to fall enzymatic medication. "If vaccine of liver of remedial sex second develops a success, face will be a huge market. " a personage inside the industry not without hopeful. Nevertheless, negotiable securities Zou enters an ancient name for China newly to express, vaccine of liver of remedial sex second sees a risk at present bigger, the person that the likelihood suits those risk preferences. In addition, those who deserve attention is, the research of countrywide hepatitis vaccine that held in Chengdu in November 2006 and applied experience communication are met on, advocate the liver of remedial sex second that this great expectations be expressinged by the market did not allude almost in the report is vaccinal. (the exercitation edits: Plum apricot)