Wednesday, 11 July 2007
Accord with 3 conditions to just can fight virus to treat
1. The second liver patient that via examining the numerical value of DNA of virus of its second liver is more than milliliter of 105 copies / should undertake disease-resistant poison is treated; Antigen of second liver E shows electronegative second liver " small 3 this world " patient, when the numerical value that is like DNA of virus of its second liver is more than milliliter of 104 copies / , also should undertake disease-resistant poison is treated. 2. The second liver patient that via examining transaminase of its cereal third is more than 80 units / to rise should undertake disease-resistant poison is treated; But the patient that use interferon has fighting virus remedial, transaminase of its cereal third should rise in 400 units / the following, in the meantime, level of its serum total bilirubin also should is less than 35 small rub Er / rises, use interferon cure to bring about its illness accentuation likely otherwise. 3. Liver function is spent gently unusual, but examination of classics liver histology shows its Knodell HAI is more than 4 minutes, or the second liver patient that via liver organization vivid check shows 2 degrees to necrotic degree is more than its inflammation should undertake disease-resistant poison is treated. Be worth what carry is, have the 1st patient, if have the 2nd at the same time or the 3rd more should actively undertakes disease-resistant poison is treated, notice to monitor the change of the illness even in cure. If DNA of second liver virus shows masculine gender continuously, and transaminase of its cereal third is unusually elevatory (should eliminate by the cereal third of medicaments, alcohol and other factor be caused by transaminase is lifted) , also should consider to undertake disease-resistant poison is treated. If second liver virus of the patient is duplicate index (DNA of second liver virus or antigen of second liver E) for negative, or because take medicine, fat or when sufferring from the element such as fatty liver to cause transaminase to lift, do not accord with the requirement that has fighting virus remedial. If cereal third transaminase of the patient is original taller, because the near future was used,just fall enzymatic medicaments and make its it is normal that this index restored temporarily, below this kind of circumstance the patient should undertake disease-resistant poison is treated. Still have a few special case, be like liver cirrhosis patient, although transaminase of its cereal third is not tall, dan Jigu careless transaminase is apparently elevatory however, below this kind of circumstance, the patient also needs to undertake disease-resistant poison is treated. Second liver " big 3 this world " how should the patient undertake disease-resistant poison treats second liver " big 3 this world " , what say on medicine namely " the chronic hepatitis B of positive of antigen of second liver E " . It is to show antigen of second liver surface, E antigen and core antibody all show masculine gender. Right now, of DNA of second liver virus detect the result is masculine gender. Second liver " big 3 this world " transaminase is like serum cereal third of the patient to last or lift repeatedly, or when classics liver histology checks his to have hepatitis pathological change, should emphasize undertake disease-resistant poison is treated. To its the ration of DNA of second liver virus is more than transaminase of third of milliliter of 105 copies / , its cereal to be more than 80 units / to rise, or transaminase of its cereal third is less than 80 units / to rise, but examination of classics liver histology shows its Knodell HAI is more than 4 minutes, or the patient that via liver organization vivid check shows 2 degrees to necrotic degree is more than its inflammation, should undertake disease-resistant poison is treated. Undertaking disease-resistant poison treats Shi Kegen to occupy particular case of the patient, choose common α interferon (IFN α ) or nucleotide (acerbity) analogue. For example, when the cereal third transaminase that becomes a patient is less than 400 units / to rise, can choose common. Interferon. DNA of virus of its second liver shows masculine gender but this are mensurable the patient under milliliter of 105 copies / , after to its the illness monitors 3 months, if DNA of virus of its second liver still did not turn shade, and when transaminase of its cereal third is unusual also, should undertake disease-resistant poison is treated. Second liver " big 3 this world " the medicaments that when the patient is undertaking disease-resistant poison treats, can choose and its usage are as follows: 1. Common α interferon: Patient but every time hypodermic or intramuscular injection this medicine 5 1 million units, also but according to oneself be able to bear or endure suffer a circumstance to adjust dosage appropriately, inject 3 times every week or tertian inject, a period of treatment is 6 months about. The patient has through be like after such cure respondent (have curative effect) , also can lengthen period of treatment to a year to heighten curative effect or a few longer time. But what should notice to use medical dosage and period of treatment is individual change. If still be not had,treat 6 lunar hind with this medicine respondent, can convert content of other disease-resistant bane. 2. Get together glycol interferon α - 2a (PegIFN α - 2a) : Patient but every time hypodermic this medicine 180 microgramme, inject every week, a period of treatment is a year about. The patient uses the dosage of this medicine to answer according to oneself be able to bear or endure suffer the element such as degree to decide. 3. Rummy husband decides: Patient but every time profess to convinced this medicine 100 milligram, daily take 1 times. After taking this drug one year, if the patient already did not detect DNA of second liver virus (PCR law) or the index of DNA of virus of its second liver the index of transaminase of third of the floor level under unusual index, its cereal already answer often, antigen of E of its second liver already turned shade but did not appear second, need to continue to use drug, till its appear,antibody of second liver E just can consider to stop drug. After antibody of E of liver of patient occurrence second, check via two again (every time at least removed 6 months) , the assay index such as antigen of E of liver of transaminase of third of the DNA of second liver virus that is like a patient, cereal, second maintains changeless ability to be able to stop drug, but the patient after stopping drug still needs to monitor these assay quota closely. 4. Ester of A Defu Wei: Patient but every time profess to convinced this medicine 10 milligram, daily take, when to stop medicine to should consult the condition stopping drug that rummy husband decides. 5. Favour for Ka Wei: Patient but every time profess to convinced this medicine 0. 5 milligram (to rummy husband calm generation is able to bear or endure property of a medicine person goluptious take 1 milligram) , daily take, when to stop medicine to also should consult the condition stopping drug that rummy husband decides. Second liver " small 3 this world " how should the patient undertake disease-resistant poison treats second liver " small 3 this world " , what say on medicine namely " the chronic hepatitis B of negative of antigen of second liver E " . Antibody of antigen of this second liver surface of ill patient, E and core antibody all show masculine gender. DNA of virus of its second liver also is such patient transaminase shows third of electropositive, its cereal to last or relapse unusual position, examinations of some histology of liver of classics of this kind of patient have hepatitis pathological change. If " small 3 this world " ration of DNA of second liver virus is more than 104 copies transaminase of third of / milliliter, its cereal is more than 80 units / to rise; Or transaminase of its cereal third is less than 80 units / to rise, but examination of classics liver histology shows its Knodell HAI is more than 4 minutes, or when via liver organization vivid check shows 2 degrees to necrotic degree is more than its inflammation, should undertake disease-resistant poison is treated. Because decide the end time that this disease treats hard, so, "Small 3 this world " the patient wants cure to come normally do not detect DNA of virus of liver giving second (PCR law) till with its cereal third transaminase returns to normal. The illness recrudesce rate of this disease patient is high, remedial time is longer also (it is a year at least) , accordingly, this disease patient had better choose common α interferon (IFN α ) , especially the patient that cereal third transaminase is less than 400 units / to rise should be done so more. If this cereal third transaminase of ill patient is more than 400 units / to rise, or the person that its serum bilirubin lifts, had better not choose interferon. Such patient can choose ester of A Defu Wei or favour to wait for Ka Wei be able to bear or endure the nucleotide with inferior occurence rate of property of a medicine (acerbity) analogue. Short of afore-mentioned person that treat a standard, answer to monitor the change of the illness closely. If the patient discovers DNA of his second liver virus shows masculine gender continuously, and when cereal third transaminase is unusual, also should consider to undertake disease-resistant poison is treated. Second liver " small 3 this world " the medicaments that when the patient is undertaking disease-resistant poison treats, can choose and its usage are as follows: 1. Common α interferon (IFN α ) : Patient but every time hypodermic or intramuscular injection this medicine 5 1 million units, inject 3 times every week or tertian inject, a period of treatment is a year at least. 2. Get together glycol interferon α - 2a (PegIFN α - 2a) : Patient but every time hypodermic this medicine 180 microgramme, inject every week, a period of treatment is a year at least. 3. Ester of A Defu Wei: Patient but every time profess to convinced this medicine 10 milligram, daily take, a period of treatment is a year at least. After period of treatment ends, need to check 3 times (every time at least removed 6 months) , be less than via if DNA of second liver virus detects,checking (PCR law) or its index the floor level under normal index, and when transaminase of its cereal third returns to normal, can stop drug. 4. Rummy husband decides: Patient but every time profess to convinced this medicine 100 milligram, daily take, a period of treatment is a year at least, when to stop medicine to should consult the condition stopping drug of ester of A Defu Wei. 5. Favour for Ka Wei: Patient but every time profess to convinced this medicine 0. 5 milligram (to rummy husband calm generation is able to bear or endure property of a medicine person goluptious take 1 milligram) , daily take, when to stop medicine to should consult the condition stopping drug of ester of A Defu Wei. Those who need a specification is, rummy husband is decided, ester of A Defu Wei, favour belongs to nucleotide together for Ka Wei kind disease-resistant bane, the treats with poison of disease-resistant of Yu Yi liver delegate medicaments that is different period. These a few kinds of medicaments have common characteristic, for example, the effectiveness that they fight virus is stronger, wait without apparent side effect. But the patient also needs to note a few problems when taking this kind of medicaments, if take the period of treatment of this medicine to grow, the patient should have the preparation that takes drug for a long time, and cannot stop drug easily, once stop drug,have a relapse likely. To this patient's due and sober understanding. (responsibility edits: King sea E)
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